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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Epidemiology. 2017 May;28(3):365–369. doi: 10.1097/EDE.0000000000000606

Table 2.

Fixed effects of time left unrefrigerated and freeze–thaw cycle(s) on measured thyroid hormone biomarkers in plasma of pregnant women

Time Left Unrefrigerateda Freeze–Thawa Interaction between time and freeze–thawb
Fixed effect 95% Confidence Interval Fixed effect 95% Confidence Interval Fixed effect 95% Confidence Interval
TT3 1.35 0.01, 2.66 0.41 −2.07, 2.72 −0.88 −4.08, 2.17
T3 uptake 0.12 −0.36, 0.26 −0.06 −0.06, 0.28 0.29 −0.13, 0.77
TT4 0.03 −0.04, 0.10 −0.05 −0.16, 0.05 0.05 −0.10, 0.21
TSH 0.01 −0.01, 0.02 −0.01 −0.02, 0.00 −0.01 −0.03, 0.02
TPO-Abc 0.001 −0.01, 0.02 −0.02 −0.02, −0.01 0.04 −0.01, 0.10
a

Model includes only fixed effect of time left unrefrigerated (ordinal categorical) or freeze–thaw (dichotomous) respectively.

b

Model includes fixed effects of time left unrefrigerated, freeze-thaw, and time*freeze thaw interaction term.

c

The variable was natural log-transformed to approximate normal distribution