Table 2.
Baseline characteristics and medication use in patients with AF-related incident ischaemic stroke in OXVASC and OCSP
| OCSP (1981-86; n=85) | OXVASC (2002-2012; n=383) | p | |
|---|---|---|---|
| Baseline characteristics | |||
| Male sex (%) | 39 (45.9) | 171 (44.6) | 0.836 |
| Mean age (SD) | 77.3 (9.0) | 80.0 (9.7) | 0.016 |
| Premorbid risk factor | |||
| Congestive cardiac failure | 17 (20.0) | 99 (25.8) | 0.259 |
| Hypertension | 61 (71.8) | 282 (73.6) | 0.725 |
| Age≥75 | 52 (61.2) | 280 (73.1) | 0.028 |
| Diabetes | 14 (16.5) | 58 (15.1) | 0.759 |
| Previous TIA | 22 (25.9) | 60 (15.7) | 0.025 |
| Previous MI | 15 (17.6) | 72 (18.8) | 0.805 |
| Angina | 13 (15.3) | 102 (26.6) | 0.028 |
| Current smoking | 22 (25.9) | 30 (7.8) | <0.0001 |
| Hypercholesterolaemia# | 39 (45.9) | 118 (30.8) | 0.008 |
| Peripheral vascular disease | 8 (9.4) | 56 (14.6) | 0.206 |
| Valvular heart disease | 22 (25.9) | 82 (21.4) | 0.370 |
| Premorbid medications | |||
| Antiplatelet agent(s) | 8 (9.4) | 202 (52.7) | <0.0001 |
| Lipid lowering agent | 0 | 102 (26.6) | <0.0001 |
| Antihypertensive(s) | 19 (22.4) | 280 (73.1) | <0.0001 |
| Anticoagulant | 3 (3.5) | 47 (12.3) | 0.018 |
#
defined as ≥6.0 mmol/l