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. 2017 Jan 26;9(3):476–489. doi: 10.1080/19420862.2017.1285479

Table 1.

Concentration dependent viscosity data on 16 mAbs used in this study.*

Name C20 η (cP) C50 η (cP) C60 η (cP) C75 η (cP) C100 η (cP) C125 η (cP) C150 η (cP) C175 η (cP) C200 η (cP)
mAb1 19 1.1 ± 0.0 49 1.5 ± 0.0         98 2.6 ± 0.0 126 3.7 ± 0.0 153 5.4 ± 0.1 172 8.0 ± 0.1 204 13.5 ± 0.2
mAb2 18 1.2 ± 0.0 52 1.6 ± 0.0         97 2.7 ± 0.0 127 3.7 ± 0.1 149 5.4 ± 0.1 171 8.1 ± 0.2 195 13.3 ± 0.7
mAb3 23 1.2 ± 0.0 46 1.5 ± 0.0         95 2.9 ± 0.1 126 4.0 ± 0.0 148 6.2 ± 0.1 171 11.1 ± 0.6 198 19.1 ± 3.7
mAb4     51 1.9 ± 0.4         102 2.9 ± 0.0 133 4.7 ± 0.5 161 6.8 ± 0.2     198 21.3 ± 0.4
mAb5 19 1.1 ± 0.0 45 1.4 ± 0.0         99 2.7 ± 0.0 126 4.1 ± 0.1 147 6.6 ± 0.1 176 12.2 ± 0.6 196 20.4 ± 0.9
mAb6 21 1.2 ± 0.0 48 1.7 ± 0.0     74 2.3 ± 0.0 98 3.3 ± 0.0 129 5.3 ± 0.0 150 8.4 ± 0.1 175 14.1 ± 0.2 203 28.9 ± 0.8
mAb7 19 1.2 ± 0.0 46 1.7 ± 0.0         101 3.7 ± 0.0 124 6.1 ± 0.0 150 10.7 ± 0.3 176 19.2 ± 0.6 206 39.1 ± 2.4
mAb8 17 1.2 ± 0.0 43 1.5 ± 0.0     91 3.3 ± 0.0 114 5.0 ± 0.1 137 8.3 ± 0.1 160 14.5 ± 1.1     189 33.0 ± 2.7
mAb9 25 1.3 ± 0.0 49 1.7 ± 0.0         105 3.9 ± 0.0 127 6.9 ± 0.0 153 12.9 ± 0.1 183 27.6 ± 0.2    
mAb10 25 1.3 ± 0.0 50 1.7 ± 0.0         107 4.2 ± 0.1 134 7.6 ± 0.1 155 15.6 ± 0.6     191 44.9 ± 1.8
mAb11 19 1.1 ± 0.0 53 1.5 ± 0.0         96 3.2 ± 0.2 125 6.4 ± 0.6 150 13.9 ± 0.5 170 27.3 ± 4.5    
mAb12 18 1.2 ± 0.0 46 1.6 ± 0.0         99 4.0 ± 0.0 126 7.0 ± 0.1 148 13.7 ± 0.2 172 31 ± 0.6 212 113 ± 2.7
mAb13 20 1.3 ± 0.0 40 1.9 ± 0.0 61 3.1 ± 0.03 83 5.8 ± 0.0 102 11.0 ± 0.1 126 28.9 ± 3.2 132 33.5 ± 2.4        
mAb14 20 1.6 ± 0.0 41 3.4 ± 0.0 62 7.5 ± 0.03 81 15.4 ± 0.1 106 30.2 ± 0.2 130 57.9 ± 0.5 150 103.6 ± 1.0        
mAb15     51 1.9 ± 0.0         91 5.0 ± 0.0 122 13.2 ± 2.2 149 29 ± 2.9 172 70.5 ± 0.6 199 226 ± 16.0
mAb16 19 1.2 ± 0.0 52 2.5 ± 0.0         103 15.4 ± 0.2 131 43.6 ± 0.6 149 94.7 ± 0.6        
*

A total of 105 concentration-antibody measurements were performed. Each viscosity value is an average of 3 independent measurements.