Table 3.
Thyroid Hormone Levels and Bone Metabolic Markers Before and After Thyroidectomy in the Patients Whose Serum Intact PTH Levels Were >10 pg/mL One Day After Thyroidectomy
| Patient subgroups | ||||||
|---|---|---|---|---|---|---|
| TSH ≤0.03 μIU/mL (n = 28) | 0.03 < TSH ≤0.3 μIU/mL (n = 24) | 0.3 < TSH ≤5 μIU/mL (n = 19) | ||||
| Parameter | Before | After | Before | After | Before | After |
| TSH (μIU/mL) | 1.82 (1.30) | 0.01 (0.01)*c | 1.58 (2.05) | 0.10 (0.08)c | 1.55 (1.20) | 1.61 (1.18) |
| fT4 (ng/dL) | 1.06 (0.12) | 1.54 (0.20)*c | 1.10 (0.13) | 1.44 (0.15)c | 1.13 (0.13) | 1.36 (0.20)c |
| fT3 (pg/mL) | 2.80 (0.31) | 3.09 (0.39)c | 2.95 (0.26) | 2.97 (0.28) | 2.92 (0.24) | 2.78 (0.22)a |
| Calcium (mg/dL) | 8.88 (0.30) | 8.74 (0.36)a | 8.78 (0.34) | 8.73 (0.39) | 8.76 (0.29) | 8.60 (0.30)a |
| Intact PTH (pg/mL) | 39.4 (12.5) | 32.2 (13.4)a | 38.3 (11,2) | 34.2 (11.4) | 40.1 (11.5) | 31.9 (12.1)b |
| TRACP-5b (mIU/dL) | 377 (142) | 371 (133) | 361 (203) | 328 (183) | 362 (162) | 319 (139)a |
| BAP (μg/dL) | 13.4 (3.8) | 15.6 (5.1)b | 13.7 (7.5) | 13.4 (6.4) | 14.9 (6.3) | 14.3 (6.0) |
TSH is shown as median (IQR). Other parameters are shown as mean (SD).
a
p < 0.05; bp < 0.01; cp < 0.001.
Statistical significance (before vs. after thyroidectomy) was analyzed by paired t-test or by *Wilcoxon signed rank test.
PTH, parathyroid hormone; TRACP-5b, tartrate-resistant acid phosphatase isoform 5b; BAP, bone alkaline phosphatase.