Figure 3. FAM84B upregulation associates with PC tumorigenesis.

Data were extracted from GDS2546 (Gene Expression Omnibus) (A), and Oncomine^TM (Compendia Bioscience, Ann Arbor, MI) datasets Taylor (B), Grasso (C), Lapointe (D), and Vanaja (E) for analysis of changes in FAM84B mRNA. Mean ± SD are graphed. *p < 0.05 by a 2-tailed Student's t-test in comparison to Normal; ^#p < 0.05 in comparison to primary PC (2-tailed Student's t-test). (F–H) A receiver-operating characteristic (ROC) curve of primary prostate tumors versus metastatic PCs was derived from the indicated datasets. AUC: area under the curve.