Figure 8. NQO1 expressing MCF7 cells show a significant increase in mitochondrial oxygen consumption and mitochondrial ATP production.

The Seahorse XF96 analyzer was employed to determine the status of mitochondrial function in MCF-7-LV105 cells (empty vector) and MCF-7-NQO1 cells after 48 hours. A. A representative line graph of 3 independent experiments is shown. B. Respiration (basal and maximal), as well as ATP levels, were significantly increased. * p < 0.05; ** p < 0.005.