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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Neuropharmacology. 2017 Jan 23;117:49–60. doi: 10.1016/j.neuropharm.2017.01.020

Figure 3. Knockdown of GSK3β in the NAcSh increases cocaine self-administration.

Figure 3

A. Effect on acquisition of cocaine self-administration. Mean (±SEM) number of infusions of cocaine in control or shGSK3β rats self-administering 0.2mg/kg/inf cocaine. B. Effect on maintenance of cocaine self-administration. Mean (±SEM) number of infusions of cocaine in control or shGSK3β rats of 0.5mg/kg/inf cocaine for 2 hr/session. C. Dose response function of self-administration. Mean (±SEM) intake (mg/kg) of cocaine at each dose (30 min ea). (n=10–11) *Significant difference from controls, p<0.05.