Skip to main content
letter
. 2016 Nov;101(11):e440–e444. doi: 10.3324/haematol.2016.149278

Figure 2.

Figure 2.

IL-6 signaling is not required for the initial pro-inflammatory cytokine response to stored red blood cell (RBC) transfusion in recipient mice. The 12 cytokines (from a total of 32 cytokines measured) whose expression was induced in response to transfusion with stored HOD RBCs in recipient mice are shown. Serum levels of inflammatory cytokines (as labeled) in WT and IL-6KO (6KO) C57BL/6J mice (aged 10–12 weeks) 90-min post transfusion with stored HOD RBCs compared to untransfused mice (Un) measured through bead-based Luminex assay. Combined data from 3 independent experiments. Bars on scatter plots represent median values. *P<0.05; **P<0.01; ***P<0.001; ****P<0.0001; ns=P>0.05.