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. 2016 Dec 1;102(4):666–675. doi: 10.3324/haematol.2016.154245

Figure 2.

Figure 2.

Lag plots of relative risks of hospital admissions for sickle cell disease according to exposure to environmental factors. The lag plots of relative risks (RR) and 95% confidence intervals (CI) per standard deviation (SD) increase in 17 exposure variables (8 for meteorological conditions and 9 for air quality) are based on distributed lag non-linear models with all lags (0–7 days) modeled together using a polynomial constraint for sickle cell anemia (HbSS) admissions in London (red) and Paris (blue) between 1st January, 2008 and 31st December, 2012. Panel A shows variables with statistically significant associations, while panel B shows those with non-statistically significant associations. Statistically significant risks are shown in a brighter red or blue for London and Paris, respectively. Data on black carbon and particle number were not available for Paris.