Table 2.

Top 5 Gene Ontology Terms for Hyper-DhMRs.

Gene Ontology Term	FDR P-value	**Gene Symbols
*Generation of neurons	0.00000000509	Mycbp2, Foxp1, Braf, Arhgef28, Ank3, Rnd2, Arsb, Atoh1, Prdm1, Bmp2, Bmpr1a, Runx2, Cdh11, Epha3, Epha4, Etv1, Gdnf, Gfra1, Lpar1, Hgf, Hhip, Ifrd1, Il2, Itgb1, Kif5b, Lama2, Man2a1, Mllt4, Trpm1, Map2, Ncam1, Ctnnd2, Ntrk3, Nr4a2, Enpp2, Prkg1, Prox1, Ptprd, Ptprm, Rheb, Robo1, Sema6a, Slit2, Sox14, Sox5, Cpeb3, Stxbp1, Arfgef1, Tcf4, Zeb1, Zfp521, Psd3, Tenm2, Tenm3, Kif20b, Prickle2, Rgma, Lsamp, Negr1, Slitrk3, Rgs6, Magi2, Park2, Corin, Golga4, Dfna5, Rapgef4, Gsk3b, Cdon, Sall1, Dleu2, Hmg20a, Zswim6, Agtpbp1, Rere, Tmem106b, Prmt3, Fryl, Ispd, Sdccag8, Fgf20, Sirt1
*Nervous system development	0.0000000186	Mycbp2, Adgrb1, Foxp1, Braf, Arhgef28, Ank3, Rnd2, Arsb, Atoh1, Prdm1, Bmp2, Bmpr1a, Runx2, Cdh11, Epha3, Epha4, Etv1, Gdnf, Gfra1, Lpar1, Grik1, Hgf, Hhip, Hspg2, Ifrd1, Il2, Itgb1, Kif5b, Lama2, Man2a1, Mllt4, Trpm1, Map2, Ncam1, Nfia, Ctnnd2, Nrxn1, Nrxn3, Musk, Ntrk3, Nr4a2, Otx1, P2ry1, Enpp2, Prkg1, Prox1, Ptprd, Ptprm, Rheb, Robo1, Nptn, Sema6a, Slit2, Sox14, Sox5, Cpeb3, Stxbp1, Arfgef1, Tcf4, Zeb1, Alx1, Ttn, Zfp521, Psd3, Tenm2, Tenm3, Kif20b, Prickle2, Rgma, Mcph1, Rpgrip1l, Rbfox1, Lsamp, Negr1, Slitrk3, Rgs6, Magi2, Park2, Corin, Golga4, Dfna5, Cadm1, Rapgef4, Gsk3b, Cdon, Sall1, Dleu2, Hmg20a, Zswim6, Agtpbp1, Rere, Dpf3, Tmem106b, Prmt3, Fryl, Kif1bp, Ispd, Sdccag8, Hdac9, Fgf20, Sirt1
*Neurogenesis	0.0000000186	Braf, Agtpbp1, Ank3, Arfgef1, Arhgef28, Arsb, Atoh1, Bmp2, Bmpr1a, Cdh11, Cdon, Corin, Cpeb3, Ctnnd2, Dfna5, Dleu2, Enpp2, Epha3, Epha4, Etv1, Fgf20, Foxp1, Fryl, Gdnf, Gfra1, Golga4, Gsk3b, Hgf, Hhip, Hmg20a, Ifrd1, Il2, Ispd, Itgb1, Kif20b, Kif5b, Lama2, Lpar1, Lsamp, Magi2, Man2a1, Map2, Mllt4, Mycbp2, Ncam1, Negr1, Nr4a2, Ntrk3, P2ry1, Park2, Prdm1, Prickle2, Prkg1, Prmt3, Prox1, Psd3, Ptprd, Ptprm, Rapgef4, Rere, Rgma, Rgs6, Rheb, Rnd2, Robo1, Runx2, Sall1, Sdccag8, Sema6a, Sirt1, Slit2, Slitrk3, Sox14, Sox5, Stxbp1, Tcf4, Tenm2, Tenm3, Tmem106b, Trpm1, Zeb1, Zfp521
Cell Development	0.0000000366	Camk2d, Abi1, Agfg1, Akap6, Alx1, Ank3, Arfgef1, Arhgef28, Arid4a, Arsb, Atoh1, Bin3, Bmp2, Bmpr1a, Braf, Cdh11, Cdon, Cnot2, Col11a1, Cpeb3, Ctnnd2, Dleu2, Enpp2, Epha3, Epha4, Etv1, Fermt2, Foxp1, Fryl, Gdnf, Gfra1, Golga4, Gsk3b, Hdac9, Hgf, Hmg20a, Hspa2, Ifrd1, Il2, Impad1, Ispd, Itga4, Itgb1, Kif20b, Kif5b, Klf5, Lama2, Lims1, Lpar1, Lsamp, Magi2, Maml1, Man2a1, Map2, Megf10, Mllt4, Mycbp2, Ncam1, Negr1, Nr4a2, Ntrk3, Park2, Prdm1, Prickle2, Prkg1, Prmt3, Prox1, Ptprd, Ptprm, Rap1b, Rapgef4, Rdx, Rere, Rgma, Rgs6, Rheb, Rnd2, Robo1, Runx2, S1pr3, Sall1, Sema6a, Sirt1, Slc8a1, Slit2, Slitrk3, Smyd3, Sox14, Sox5, Stxbp1, Tcf4, Tenm2, Tenm3, Tmem106b, Trpm1, Trps1, Ttn, Zeb1, Zfp42, Zswim6
*Neuron differentiation	0.0000000366	Mycbp2, Foxp1, Braf, Arhgef28, Ank3, Rnd2, Arsb, Atoh1, Prdm1, Bmp2, Runx2, Cdh11, Epha3, Epha4, Etv1, Gdnf, Gfra1, Lpar1, Hgf, Ifrd1, Il2, Itgb1, Kif5b, Lama2, Trpm1, Map2, Ncam1, Ctnnd2, Ntrk3, Nr4a2, Prkg1, Prox1, Ptprd, Ptprm, Robo1, Sema6a, Slit2, Sox5, Cpeb3, Stxbp1, Arfgef1, Tcf4, Zeb1, Zfp521, Psd3, Tenm2, Tenm3, Kif20b, Prickle2, Rgma, Negr1, Slitrk3, Rgs6, Magi2, Park2, Corin, Golga4, Dfna5, Rapgef4, Gsk3b, Cdon, Sall1, Dleu2, Hmg20a, Zswim6, Agtpbp1, Rere, Tmem106b, Prmt3, Fryl, Ispd, Fgf20, Sirt1

^*Indicates neuronal-related pathway as previously determined by Geigman et al., 2010

^**Bolded gene symbols indicate known stress-related genes from the GeneCards database.