Skip to main content
. 2017 Feb 11;8(13):20602–20611. doi: 10.18632/oncotarget.15292

Figure 2. The effects of caffeine on the spindle morphology during oocyte aging.

Figure 2

A. Spindle morphology of fresh oocytes, caffeine-treated oocytes and oocytes aged in vitro. B. Percentage of oocytes with intact and abnormal spindles in fresh oocytes, caffeine-treated oocytes and oocytes aged in vitro. All graphs show mean ± s.e.m. Abbreviations used in this and all subsequent figures: CA, caffeine treated; IVA, in vitro aging. a-c: Values without a common letter in their superscripts differ significantly (P < 0.05). Spindle (green) and chromosomes (blue). The white arrows indicate the spindle defects and chromosome misalignment. Bar, 20 μm.