Figure 1. The addition of celecoxib enhances the capacity of cetuximab to inhibit cell proliferation and to induce apoptosis in colorectal cancer cells.

A. Cell proliferation and, B. The fraction of apoptotic cells was evaluated after 72h of treatment with cetuximab (CTX, 100 μg/ml) alone or in combination with different doses (10 μM and 50 μM) of celecoxib (CXB). Data are means ± SEM of three independent experiments (*p <0.05, compared with the control; # p<0.05, compared with cetuximab-treated cells).