Figure 9. The nuclear expression of FOXM1 in colon cancer is significantly associated with a better rate of response in patients treated with cetuximab.

A. The expression of β-catenin and FOXM1 was analyzed by immunohistochemistry (IHC) in 25 human colorectal cancer tumors. Representative images of IHC and hematoxylin-eosin (H-E) stainings of tumors are shown. Original magnification: X20. B. The association between the nuclear localization of FOXM1 and response to treatment was assessed by a chi-square test. p values were considered significant if they were < 0.05.