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Journal of the Royal College of Physicians of London logoLink to Journal of the Royal College of Physicians of London
. 1994 Sep-Oct;28(5):411–414.

Endoscopy: Throat Spray or Sedation?

Stephen P Pereira 1, S Hyder Hussaini 2, Peter J V Hanson 3, Mark L Wilkinson 4, Gordon E Sladen 5
PMCID: PMC5401026  PMID: 7807428

Abstract

Anxious patients tolerate endoscopy poorly. It was proposed that such patients might derive most benefit from sedation, while most non-anxious patients would prefer endoscopy with lignocaine throat spray alone. In a prospective study, 200 outpatients underwent diagnostic endoscopy after receiving one of two detailed information sheets which offered them either the choice between spray or sedation (n = 100) or the same choice but encouraged those who were anxious about endoscopy to choose sedation (n = 100). When given an informed choice, most non-anxious patients prefer not to be sedated during diagnostic endoscopy. If patients who are anxious about the procedure are advised to choose sedation, those who nevertheless opt for topical throat spray alone find the endoscopy just as comfortable. If the endoscopy were to be repeated, 73% of the spray group and 77% of the sedation group would make the same choice again. Of 33 patients who chose spray but had been given only sedation for a previous endoscopy, 26 (79%) would choose spray again for a future endoscopy. The choice of spray or sedation should reflect the patient's view as well as that of the endoscopist.

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Contributor Information

Stephen P Pereira, Research Registrar, Division of Medicine, UMDS of Guy's and St Thomas' Hospitals, London.

S Hyder Hussaini, Research Registrar, Division of Medicine, UMDS of Guy's and St Thomas' Hospitals, London.

Peter J V Hanson, Senior Registrar, Division of Medicine, UMDS of Guy's and St Thomas' Hospitals, London.

Mark L Wilkinson, Senior Lecturer, Division of Medicine, UMDS of Guy's and St Thomas' Hospitals, London.

Gordon E Sladen, Consultant Physician and Gastroenterologist, Division of Medicine, UMDS of Guy's and St Thomas' Hospitals, London.


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