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Journal of the Royal College of Physicians of London logoLink to Journal of the Royal College of Physicians of London
. 1996 Nov-Dec;30(6):497–504.

Chronic Fatigue Syndrome

Summary of a Report of a Joint Committee of the Royal Colleges of Physicians, Psychiatrists and General Practitioners

Simon Wessely 1
PMCID: PMC5401495  PMID: 8961200

Abstract

Chronic Fatigue Syndrome (CFS) is not a single diagnostic entity. It is a symptom complex which can be reached by many different routes. The conceptual model of CFS needs to be changed from one determined by a single cause/agent to one in which dysfunction is the end stage of a multifactorial process. Although it is important to recognise the role of factors that precipitate the condition, greater understanding is required of factors that predispose individuals to develop the illness, and those that perpetuate disability.

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