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Inflammation from the tumor propagates to the liver and brain. Tumor tissue expressed high mRNA levels for IL6, IL1β, and TNFα compared to healthy tissue (A). Within tumor-bearing mice, this local inflammation resulted in increased IL6, IL1β, and CD11b mRNA expression in the liver (B) and increased IL1β mRNA within all brain regions tested (C–G). n=6–8/mice group. * p<0.05
