Outcomes of Surgeries Performed in Physician Offices Compared With Ambulatory Surgery Centers and Hospital Outpatient Departments in Florida

Abstract

Background:

The proportion of outpatient surgeries performed in physician offices has been increasing over time, raising concern about the impact on outcomes.

Objective:

To use a private insurance claims database to compare 7-day and 30-day hospitalization rates following relatively complex outpatient surgical procedures across physician offices, freestanding ambulatory surgery centers (ASCs), and hospital outpatient departments (HOPDs).

Methods:

A multivariable logistic regression model was used to compare the risk-adjusted probability of hospitalization among patients after any of the 88 study outpatient procedures at physician offices, ASCs, and HOPDs over 2008-2012 in Florida.

Results:

Risk-adjusted hospitalization rates were higher following procedures performed in physician offices compared with ASCs for all procedures grouped together, for most procedures grouped by type, and for many individual procedures.

Conclusions:

Hospitalizations following surgery were more likely for procedures performed in physician offices compared with ASCs, which highlights the need for ongoing research on the safety and efficacy of office-based surgery.

Introduction

The number of outpatient surgeries performed in physician offices in the United States has risen dramatically over the past 30 years, increasing from about 110 000 procedures in 1981 to 12 million procedures in 2009.^1,2 Growth in office-based surgical procedures is attributable to a number of factors, most notably physicians seeking greater autonomy, technological advances making office-based surgery feasible for more procedures, as well as the potential to enhance physician office revenue.^3,4

There have been some concerns, however, regarding the quality of surgical procedures provided in physician offices relative to more fully equipped and staffed hospital outpatient department (HOPD) and ambulatory surgery center (ASC) settings. Although some studies based on state-level adverse event reporting systems have not revealed any major quality problems, studies with more rigorous study designs have uncovered some quality differences between surgical procedures performed in physician offices and other outpatient settings.

In this article, we build on the existing research on outcomes for office-based surgery, as summarized in the “Background” section. Specifically, we conduct a retrospective study of the likelihood of hospitalization following outpatient surgery in Florida, from 2008 through 2012, using a large private insurance claims database. Our study compares the risk-adjusted rates of all-cause hospitalizations occurring within 7 and 30 days after procedure across facility type (physician offices, ASCs, or HOPDs) for one of the 88 relatively complex outpatient surgical procedures included in the study.

Background

Conceptual context

There are important differences between physician office-based surgery and surgery performed in ASCs and HOPDs, in several dimensions: (1) regulation, (2) surgeon volume and learning, (3) credentialing and peer review, and (4) facilities and equipment. Concerns about the safety and efficacy of office-based surgery are largely predicated on these differences.^5–10

Physician office-based surgery is largely unregulated, with fewer requirements for adverse event reporting, risk management, and quality improvement processes in physician offices as opposed to ASCs and HOPDs.^7,11 Regulation does not guarantee safer or better outcomes, but it does establish uniform minimum standards and reporting requirements which are generally designed to reduce variation in practice patterns and improve adherence to best clinical practices.^12–14

Surgeon volume and learning-by-doing are also likely to play an important role in differential outcomes between physician offices and more intensive settings.¹⁵ One of the defining characteristics of office-based surgery is that it is less resource intensive. But lower resource intensity can also limit the number of surgeries that can be performed in the office setting, which in turn may lessen the ability of office-based surgeons to capture the learning-by-doing benefits of higher volume. Lower volumes are likely to affect other members of the surgery team; in physician offices where surgery is largely a part-time activity, it may be difficult to attract higher quality anesthesiologists and surgical assistants.

A related and important difference between offices and other settings is that office-based surgeons are generally not subject to detailed credential review, in contrast to surgeons seeking access to surgical facilities at an ASC or HOPD.¹⁶ They are also less likely to be subject of a formal review process for their adverse outcomes, particularly for office-based surgeons practicing solo or in small groups, where even informal peer review is less likely to occur. Moreover, office surgeons are the prime authority in their surgical suite; the checks and balances that are normally present in ASCs and HOPDs may or may not be present in office settings (eg, physician offices may not have autonomous medical directors and administrators).¹⁴

The lower resource intensity of physician offices has potentially important implications for safety. Medical equipment and buildings are expensive but play an important role in clinical outcomes and safety.^7,16–18 Without a requirement to construct or equip a surgical suite according to uniform minimum standards consistent with the construction and equipping of ASCs and HOPDs, it is possible for some office-based surgical suites to be underequipped and less prepared for adverse events. Even routine equipment can also have implications for outcomes. A specific example is sterilization. Immediate-use steam sterilization (IUSS), formerly referred to as “flash sterilization” is relatively inexpensive, requires fewer instrument sets, and is commonly used in office-based surgery practices. However, IUSS has been shown to be a less effective sterilization technique than using a full-cycle sterilizer, which is the norm for ASCs and HOPDs.^19–22

Prior studies

Most existing studies of this issue do little or nothing to adjust for differences in the clinical factors affecting the risk of complications among patients who presented to different types of surgery sites. For example, a survey-based study of office-based liposuction by Housman et al²³ used data from members of the American Society for Dermatologic Surgery listed as performing liposuction. A total of 261 dermatologic surgeons provided data on 66 570 liposuction procedures. No deaths were reported. The overall serious adverse event (SAE) rate was 0.68 per 1000 cases. The SAE rates were higher for hospitals and ASCs than for nonaccredited office settings. Serious adverse event rates were also higher for tumescent liposuction combined with intravenous or intramuscular sedation than combined with oral or no sedation. However, no risk adjustment was performed in this study. Given the likelihood of higher case complexity for ASCs and HOPDs, higher observed complication rates are expected and may not indicate differences in quality across settings.

Comparative retrospective studies with more rigorous study designs incorporating some form of risk adjustment enable more meaningful conclusions about outcomes. For example, using the Florida adverse event registry data, Vila et al²⁴ found that adverse incidents occurred at a rate of 66 per 100 000 procedures in physician offices compared with 5.3 per 100 000 procedures in ASCs (relative risk = 12.4; 95% confidence interval [CI]: 9.5-16.2). Similarly, the death rate per 100 000 procedures performed was 9.2 in offices compared with 0.78 in ASCs (relative risk = 11.8; 95% CI: 5.8-24.1). The authors concluded that “if all office procedures had been performed in ASCs, approximately 43 injuries and 6 deaths per year could have been prevented.”

One of the more rigorous comparative observational studies to date is by Fleisher et al.²⁵ The authors conducted a claims analysis of patients undergoing 16 different surgical procedures in a nationally representative (5%) sample of Medicare beneficiaries (1994-1999). Mortality rates, emergency department risk, and admission to a hospital within 7 days of outpatient surgery were compared across physicians’ offices, ASCs, and HOPDs. Rates were risk-adjusted for age, sex, race, and comorbidity using multivariable logistic regression. The analytic data file contained information on 564 267 outpatient surgical procedures: 360 780 at an HOPD, 175 288 at an ASC, and 28 199 at a physician’s office. The risk-adjusted 7-day mortality rate was 35 per 100 000 outpatient procedures at physicians’ offices, 25 per 100 000 outpatient procedures at ASCs, and 50 per 100 000 outpatient procedures at HOPDs. The risk-adjusted rate of admission to a hospital within 7 days of outpatient surgery was 9.08 per 1000 outpatient procedures at physicians’ offices, 8.41 per 1000 outpatient procedures at ASCs, and 21 per 1000 outpatient procedures at HOPDs.

In this article, we expand on the analytic approach used by Fleisher et al²⁵ in several aspects beyond the use of commercial claims data rather than Medicare claims data. First, we employ a more comprehensive set of risk measures in our risk adjustment model. Second, we examine a wider range of specific outpatient surgical procedures (88 compared with 15). Finally, we use more recent data. The goal of the article is to build on existing research to expand understanding of the role of surgical facility type on outcomes of relatively complex outpatient surgical procedures.

Methods

Data

We conducted a retrospective study of surgical outcomes using a large private insurance claims database, specifically the Truven Health MarketScan Commercial Claims and Encounters Database, for Florida over the period 2008 through 2012, which was the most recent 5-year period available when this research was conducted. Florida was chosen because of its large population overall, its relatively large share of residents aged 65 years and older (19.4% compared with 14.9% for the United States in 2015), and its relatively high proportion of expenditures for physicians and other professional services (30.9% compared with the US average of 27.4% in 2009).²⁶ The MarketScan database contains individual-level, de-identified, health care claims information from employers, health plans, hospitals, Medicare, and Medicaid programs. These databases reflect the real world of treatment patterns and costs by tracking millions of patients as they travel through the health care system offering detailed information about all aspects of care. Data from individual patients are integrated from all providers of care, maintaining all health care utilization connections at the patient level.

There were thousands of different surgical procedures performed at outpatient facilities during the time period, so one of the first tasks was to reduce the number of index surgical procedures for analysis and reporting purposes. We selected outpatient procedures using the following criteria: (1) we only selected procedures that had at least 100 office-based procedure claims over 2008-2012 (ie, at least an average of 20 procedures per year) and (2) a “work relative value unit” (work RVU) of at least 4.0 (ie, relatively complex procedures).²⁷ The volume threshold was selected to eliminate procedures with an insufficient sample of office-based cases for analysis. The focus on relatively complex procedures was applied because, as noted in the “Background” section, theory predicts that differences in outcomes across types of surgery settings are least likely to be observed for low-complexity procedures.²⁸

Procedure complexity was measured using the work RVU, which is a component of the Medicare (Part B) physician payment system based on the Current Procedure Terminology (CPT) code for the procedure. The payment formula contains 3 RVU components: physician work, practice expense, and malpractice expense. A code with a higher work RVU generally takes more time, more intensity, or some combination of the 2. Thus, our underlying assumption in using the work RVU cut-off is that, in general, work RVU approximates procedure complexity. A total of 88 surgical procedures met these criteria (see Table A1 for descriptions). This represents a wider range of procedures compared with the 15 procedures included in the Fleischer et al²⁵ study.

The location of services (physician office, ASC, or HOPD) was determined by the place of service code in the claims. In addition, patients with claims for study procedures were required to have insurance coverage during the month of and the month after the procedure.

The initial study sample consisted of 4 080 800 claims with CPT codes for one of the 88 study procedures in Florida for 2008-2012. From this initial sample, 139 243 claims were excluded because the surgical facility type was not one of the 3 study facility types. After combining claims with the same patient number, CPT code, data of service, and location of service, the sample included 2 807 857 unique surgical procedures. From this total, 148 531 procedures were excluded because the patients did not have insurance coverage in both the month before and the month after surgery, leaving a final study sample of 2 757 016 procedures (see Figure 1).

Figure 1.

Sample flowchart. CPT indicates Current Procedure Terminology.

Measurement

Dependent variable

The main outcome measure used as the dependent variable in our multivariable logistic regression model was hospitalization within 7 days (or alternatively hospitalization within 30 days) of the surgical procedure index date. Postprocedure hospitalization is a standard measure of surgery outcomes^29,30 and was used as an outcome measure in the Fleisher et al²⁵ study. All-cause hospitalizations were identified based on inpatient claims with admission dates within 7 or 30 days of the selected index procedures.

Independent variables

Risk adjustment facilitates a more meaningful comparison of hospitalization rates across surgical sites, given the likelihood of differences in patient severity or complexity across surgical sites. To implement risk adjustment, in addition to categorical variables for types of surgical sites, our multivariable logistic regression model included as independent variables a comorbidity index, patient age, patient sex, Major Diagnostic Category (MDC), geographic region, employment status, and year.^31–33 The specific comorbidity index used was the Centers for Medicare and Medicaid Services-Hierarchical Condition Category (CMS-HCC), which was developed by the CMS as a summary index based on 189 medical condition indicators.³⁴ Although designed to be used for risk-adjusted payments, it has demonstrated better performance relative to the commonly used Charlson and Elixhauser indices.³⁵ In general, patients with higher scores are less healthy and therefore at higher risk of future hospitalizations.

Statistical analysis

We first performed a descriptive analysis of the extent of transition from HOPD or ASC-based settings to office-based settings for the 88 study procedures from the beginning of the study period (2008-2009) to the end of study period (2011-2012). The risk-adjusted hospitalization rates across settings were estimated by multivariable logistic regression models using Stata Version 14.2 (www.stata.com). A Huber-White robust standard error estimation procedure was used to account for potential variance components when estimating standard errors, such as the potential for repeated outcome measures for the same patients (ie, some patients might have received multiple treatments for study procedures during the study period).

Three sets of logistic regression models were estimated. The first was a model with data for all 88 procedures as a pooled group. The pooled model included as independent variables a set of dummy variables for each CPT code procedure. The second is a set of models for CPT procedures grouped by the type of condition being treated (eg, CPT 40490-49999 for “Digestive” procedures). The final set of models examined each of the 88 procedure codes as separate models.

Results

Utilization by setting

Work RVU, volume, and utilization by setting for the procedure groups are shown in Table 1. The overall change in procedure setting from ASCs and HOPDs to office settings was relatively low among the procedures selected for analysis, most likely attributable to exclusion of less complex procedures (RVU < 4) that might have been most likely to move to physician offices. The total proportion of all of the 88 study procedures performed in physician office settings in the earlier period (2008-2009) was 6.7% and grew to 8.0% in the later period (2011-2012), with an aggregate change of about 1.2%.

Table 1.

Surgical procedures performed in physician offices, by surgery code group, 2008–2012.

CPT group	Group description	Mean group work, RVU	Total number of surgeries (2008–2012)	Proportion of procedures in office (2008–2009), %	Proportion of procedures in office (2011–2012), %	Proportion difference (2008/2009 to 2011/2012), %
40490–49999	Digestive	7.46	1 142 166	1.48	1.43	−0.05
20005–29999	Musculoskeletal	7.66	561 842	2.57	2.50	−0.06
56405–58999	Female genital	8.18	242 700	14.30	19.18	4.88
65091–68899	Eye and ocular adnexa	8.00	172 441	16.02	13.53	−2.49
10030–19499	Integumentary	8.91	170 769	38.85	43.49	4.64
30000–32999	Respiratory	6.24	142 968	1.07	0.91	−0.16
61000–64999	Nervous	7.49	63 974	3.22	4.85	1.64
50010–53899	Urinary	8.64	55 658	1.23	1.43	0.20
33010–37799	Cardiovascular	6.38	51 120	30.31	48.96	18.65
59000–59899	Maternity and delivery	4.84	30 499	2.93	3.60	0.67
38100–38999	Hemic and lymphatic	6.43	13 747	1.00	0.86	−0.15
69000–69979	Auditory	5.25	8132	13.78	14.81	1.03
Total			2 656 016	6.70	8.00	1.20

Abbreviations: CPT, Current Procedure Terminology; RVU, relative value unit.

Authors’ analysis of Truven MarketScan commercial claims data; see text for description.

The procedures with the highest levels of change to office settings were in the cardiovascular system group (CPT 33010-37799), increasing from 30.3% in physician offices in the earlier period (2008-2009) to nearly 50% by the later time period (2011-2012). This change was mainly due to an overall 79% increase in volume for CPT 36475 over this period, coupled with a high physician office volume share for this procedure (87%). In addition, procedures of the female genital system and integumentary system had relatively high levels of change to office settings (4.88% and 4.64%, respectively) in the period 2008-2012. Procedure volumes and the physician office share of procedures for individual procedures within CPT groupings are reported in Table A2.

Hospitalization rates

Risk adjustment models for the likelihood of hospitalization converged for a model with all of the 88 study procedures pooled together and also converged for models for 12 CPT groupings based on standard body system categories (eg, cardiovascular). Risk adjustment models also converged for 71 of the 88 individual CPT procedures. Failure to converge for the remaining 17 study procedure models was a result of a very low procedure volume for the specific procedure in 1 or more of the 3 site categories, or a very low rate of postprocedure hospitalization overall, or a combination of both. Rates of 7-day and 30-day hospitalizations were compared between office, ASC, and HOPD settings for the study of all 88 study procedures as a group, by 12 CPT groupings, and for the 71 individual procedure models. Differences in risk-adjusted rates across sites were tested for statistical significance.

All study procedures

The rates of hospital admissions (7-day and 30-day) for all 88 study procedures are reported in Table 2. The table also shows the differences between observed (unadjusted) rates and risk-adjusted rates. For the 7-day admission measure, observed rates are lowest for ASCs (0.59%), with observed rates for physician offices only slightly higher at 0.68%, and HOPD observed rates are substantially higher at 2.02%. After adjustment for the observed risk factors included in our multivariable logistic regression model (see Table A4), the office-based rate more than doubles (to 1.57%), whereas the ASC rate increases by 39% (to 0.82%) and the HOPD rate decreases by 15% (to 1.71%). The 30-day admission measure shows a similar pattern, with observed rates roughly similar for ASCs and physician offices but substantially higher for HOPDs and with risk adjustment increasing the physician office and ASC rates but reducing the HOPD rate.

Table 2.

Observed rates and risk-adjusted rate of hospital admissions within 7 and 30 days after procedure.

	7-day			30-day
	Office	ASC	HOPD	Office	ASC	HOPD
Total (N)	195 530	748 802	1 711 684	195 530	748 802	1 711 684
Overall observed rate, %	0.68	0.59	2.02	1.62	1.69	3.33
Overall risk-adjusted rate, %	1.57	0.82a	1.71a	2.72	2.03a	2.98a

Abbreviations: ASC, ambulatory surgery center; HOPD, hospital outpatient department.

Authors’ analysis of Truven MarketScan commercial claims data; see text for description.

^aDifference between rates of office setting and rates of other settings statistically significant at P ⩽ .05.

Procedure groups

A comparison of risk-adjusted hospitalization rates (7-day and 30-day post-index procedure) by setting and by procedure group is reported in Table 3. The physician office risk-adjusted 7-day hospitalization rate is higher than the ASC rate for 8 of the 12 procedure groups (P < .05), with no statistically significant difference for 3 of the procedure groups, and a higher ASC rate (P < .05) for 1 procedure group (cardiovascular). Similarly, the physician office risk-adjusted 30-day hospitalization rate is higher than the ASC rate for 8 of the 12 procedure groups (P < .05), with no statistically significant difference for 2 of the procedure groups, and a higher ASC rate (P < .05) for 2 procedure groups (cardiovascular and integumentary). Among the procedure groups with a lower risk-adjusted 30-day hospitalization rate for ASCs, the largest absolute difference is a 7.4 percentage point lower risk of ASCs in the “hemic and lymphatic” procedure group (22.3% vs 14.9%), whereas the largest proportional differences are a 83% lower rate for the “auditory” group (0.90% vs 0.15%) and a 68% lower rate for the “nervous” procedure group (5.1% vs 1.6%).

Table 3.

Risk-adjusted hospital admission rates within 7 and 30 days after the procedure.

CPT groups	Group/system	Office		ASC		HOPD
		7-day	30-day	7-day	30-day	7-day	30-day
10030–19499	Integumentary	0.25%	0.85%	0.24%	0.24%	1.25%a	2.59%a
20005–29999	Musculoskeletal	1.54%	2.08%	0.41%a	0.41%a	1.36%	2.03%
30000–32999	Respiratory	2.12%	2.27%	0.42%a	0.42%a	1.30%	2.02%
33010–37799	Cardiovascular	0.44%	2.11%	2.45%a	2.45%a	3.80%a	9.63%a
38100–38999	Hemic and lymphatic	19.90%	22.30%	6.89%a	6.89%a	8.49%a	12.50%a
40490–49999	Digestive	1.78%	3.11%	0.87%a	0.87%a	1.98%	3.48%a
50010–53899	Urinary	3.91%	6.01%	2.02%a	2.02%a	2.72%	4.59%
56405–58999	Female genital	0.96%	2.18%	0.55%a	0.55%a	3.15%a	4.29%a
59000–59899	Maternity and delivery	0.69%	0.80%	0.54%	0.54%	1.45%	1.81%a
61000–64999	Nervous	1.95%	5.10%	0.47%a	0.47%a	2.89%	4.25%
65091–68899	Eye and ocular	0.31%	1.40%	0.22%a	0.22%a	0.26%a	1.18%a
69000–69979	Auditory	0.33%	0.90%	0.09%	0.09%	0.39%	0.50%
All procedures		1.57%	2.72%	0.82%a	0.82%a	1.71%a	2.98%a

Abbreviations: ASC, ambulatory surgery center; CPT, Current Procedure Terminology; HOPD, hospital outpatient department.

Authors’ analysis of Truven MarketScan commercial claims data; see text for description.

^aDifference between rates of office setting and rates of other settings statistically significant at P ⩽ .05.

For HOPDs, the risk-adjusted 7-day and 30-day hospitalization rates were lower than the physician office rates (P < .05) for 2 procedure groups (hemic and lymphatic; eye and ocular). The risk-adjusted HOPD 7-day admission rate was higher than the physician office rate (P < .05) for 4 procedure groups, with no statistically significant difference for the remaining 8 procedure groups. Similarly, the risk-adjusted HOPD 30-day admission rate was higher than the physician office rate (P < .05) for 5 procedure groups, with no statistically significant difference for the remaining 7 procedure groups.

Specific procedures

Among the specific procedures within groupings (Table A3), the risk-adjusted rate of 7-day hospitalization for office-based procedures was greater than the ASC rate (P < .05) for 30 of the 71 individual CPT code models, with no statistically significant difference for the remaining 41 CPT models. Similarly, the risk-adjusted 30-day hospitalization rate for office-based procedures was greater than the ASC rate (P < .05) for 27 of the 71 individual CPT code models, with no statistically significant difference for the remaining 44 CPT models. None of the models indicated a statistically significant higher risk-adjusted ASC rate for either hospitalization measure.

The risk-adjusted 7-day hospitalization rate for office-based procedures was greater than the ASC rate (P < .05) for 7 of the 12 most complex procedures (work RVU > 10) and was greater than the ASC rate (P < .05) in 8 of the 12 models for the risk-adjusted 30-day hospitalization rate. In contrast, for the 12 least complex procedures included in the study (work RVU between 4.0 and 4.9), the risk-adjusted hospitalization rate for office-based procedures was greater than the ASC rate (P < .05) for 3 of the 12 models for 7-day hospitalization and for 4 of the 12 models for 30-day hospitalization.

To be conservative, statistical significance for the 71 individual procedure models was reassessed using a false discovery rate control approach suggested by Glickman et al,³⁶ as an alternative to the traditional Bonferroni adjustment for multiple comparisons. This approach entails sorting the 71 procedure models from the smallest to the largest P value for the estimated ASC coefficient and then applying an adjustment factor of (k/N) to the significance level (.05) to test the statistical significance for the kth model, where k is the rank order of the sorted models. For example, the procedure model with the smallest P value for the ASC coefficient (CPT 57288, repair bladder defect) had a P value of about 6.6e−80 (ie, a t ratio of 19.1). Applying the adjustment factor to .05 for k = 1 yields a significance criterion of .00074 (ie, .05 × (1/71)), which is larger than the P value for the ASC coefficient, so the null hypothesis of no difference is rejected. Similarly, for the procedure model with the 24th smallest P value (CPT = 20926, removal of tissue for graft), applying the adjustment factor to .05 for k = 24 yields a significance criterion of .0169 (ie, .05 × (24/71)), which in this case is smaller than the P value for the ASC coefficient (P = .0173), so the null is not rejected.

After applying this adjustment to the P < .05 significance level for all 71 procedures, the risk-adjusted rate of 7-day hospitalization for office-based procedures was statistically greater than the ASC rate for 23 of the 71 individual CPT code models, and the risk-adjusted 30-day hospitalization rate for office-based procedures was statistically greater than the ASC rate (P < .05) for 21 of the 71 individual CPT code models.

Focusing on specific procedures, the largest significant difference in outcomes between an office setting and ASC was tissue removal for graft (CPT 20926), which had risk-adjusted 7-day postsurgery hospitalization in the office setting nearly 12 times higher than that of ASCs (78.70% vs 6.59%, respectively) and 30-day hospitalization rates more nearly 11 times higher than that of ASCs (78.50% vs 7.28%, respectively). Similarly, the difference in outcomes for the same procedure was 2 times higher in an office setting compared with an HOPD setting for both risk-adjusted 7-day and 30-day hospitalizations, although the work RVU for this procedure is a relatively low 5.79.

The individual surgical procedure in which there was the largest significant difference in outcomes between an office setting and HOPD was shoulder arthroscopic surgery (CPT 29824), which had risk-adjusted 7-day postsurgery hospitalization in the office setting more than 4 times higher than that of HOPD (4.51% vs 0.94%, respectively) and 30-day hospitalization rates more than 3 times higher than that of HOPD (5.55% vs 1.67%, respectively). In addition, the same procedure had a risk-adjusted 7-day hospitalization rate in an office setting 9 times higher than that of the ASC setting (4.51% vs 0.46%, respectively) and 30-day hospitalization rate nearly 5 times higher than that of the ASC setting (5.55% vs 1.18%, respectively). The work RVU for this procedure is 8.98, which implies a more complicated and lengthy surgical process.

Discussion

Using a retrospective analysis of more than 1 million private health insurance claims in Florida from 2008 to 2012, we found high rates of change in the volume of procedures by facility type—moving from ASCs and HOPDs to physician offices—for a small number of the 88 surgical procedures examined in the analysis. However, for most of the 88 procedures, change rates were relatively low. These low observed rates of procedure volume shift to physician office settings probably reflects the focus on 88 relatively high-complexity procedures included in this study.

In addition, our analysis of risk-adjusted rates of hospitalizations following procedures performed in physician offices, ASCs, and HOPDs found significantly higher hospitalization rates after procedures performed in physician office settings compared with ASCs for most of the procedures studied. Across all 88 procedures included in the study, 7-day hospitalization rates were nearly 2 times higher for patients receiving procedures in an office setting compared with an ASC setting (P < .05). Similarly, 30-day hospitalization rates for surgical procedures performed in office settings were about 34% higher than the ASC rate for the total of 88 procedures (P < .05).

Similar, though, less consistent results were obtained for models where procedures were grouped by CPT code category or for models focused on specific procedures. Point estimates usually indicated that risk-adjusted hospitalization rates were higher for office-based procedures compared with ASC procedures, but the estimated differences were often not statistically significant, particularly for relatively low-complexity procedures.

One inconsistent finding is for the cardiovascular CPT code group, where the results indicate a statistically significant higher 7-day and 30-day hospitalization rate for ASC compared with office-based procedures. However, the cardiovascular group consisted of only 2 CPT codes: 36475, which is usually performed in physician offices (87% volume share), and 36561, which is rarely performed in physician offices (2.2% volume share), as shown in Table A2. When estimated separately, the model for CPT 36475 fails to converge, due in part to very low overall postprocedure hospitalization rates (<0.5%), which coupled with a low HOPD volume share (2.6%) results in no post-HOPD procedure hospitalizations observed in the data. The point estimate ASC coefficient in the CPT 36561 model is positive (consistent with the cardiovascular group result) but not statistically significant (see Table A3).

Another inconsistent result is for the integumentary CPT code group, where a statistically significant higher 30-day hospitalization rate for ASC compared with office-based procedures was found. The integumentary CPT code group consists of 10 CPT codes, which not only includes 5 procedures (17311, 14060, 14040, 15823, and 19350) with physician volume shares ranging from 12% to 93% and an average work RVU value of 8.0 but also includes 4 procedures (19318, 19380, 19125, and 19301) with an average work RVU value of 11 and low physician volume shares (<3%). Individual CPT code models converged for 8 of the 10 integumentary group codes, but only 2 models (19120 and 19318) had statistically significant ASC coefficients, both of which indicated lower 7-day and 30-day hospitalization rates for ASC compared with office-based procedures.

With respect to the 71 individual procedure models, the results indicated a statistically significant lower hospitalization rate for ASC compared with office-based procedures for about one-third of the 71 procedures, but none of the remaining individual procedure models indicated statistically significant differences in physician office and ASC hospitalization rates.

Taken as a whole, our results are consistent with those of Fleischer et al,²⁵ who used Medicare data to examine postsurgery hospitalization rates and mortality rates in offices, ASCs, and HOPDs. In that study, the rate of admission to an inpatient hospital within 7 days of outpatient surgery was 9.08 per 1000 outpatient procedures at physicians’ offices, 8.41 per 1000 outpatient procedures at ASCs, and 21 per 1000 outpatient procedures at HOPDs. Our study finds substantially larger differences between the physician office and ASC settings in the privately insured population, but the direction of the results across studies is consistent.

Limitations

This study has several important limitations. First, our study sample is limited to Florida and may not be representative of other states or national trends. Second, unlike Fleisher et al, the Truven MarketScan database did not support any assessment differences in mortality across settings. Instead, our analysis focused on all-cause postprocedure hospitalizations (which also were analyzed in Fleischer et al) as our outcome measure. Of course, postprocedure hospitalizations may or may not be directly attributable to the index procedures. This limitation is not as serious as it might seem because if postprocedure hospitalizations are completely unrelated to index procedures, we would expect to find no significant differences in the rates of hospitalizations between the 2 settings. Thus, any significant differences in risk-adjusted postprocedure hospitalizations that we detect across settings should be, on average, attributable to differences in some types of complication related to the index procedure across settings.

However, the occurrence of a complication ultimately resulting in hospitalization could be attributable to either errors in the process of care or specific clinical characteristics of patients placing them at higher risk of complications. As an observational study (instead of a randomized clinical trial), we cannot assume that patient risk factors were similar for patients receiving index procedures across settings. We used multivariable logistic regression to adjust for differences in observed patient risk factors among patients receiving index procedures across settings, but differences in unmeasured patient risk factors may remain. This creates the potential for bias when making inferences about differences in outcomes attributable to differences in settings.

Fortunately, we may be able to infer the potential direction of bias-based information presented in Table 2. Risk-adjusted hospitalization rates for office-based procedures were substantially higher than observed rates, whereas risk-adjusted rates were lower than actual rates for HOPDs. The ASCs fell in between, with risk-adjusted rates slightly higher than actual rates. This suggests that the lowest risk cases would tend to be treated in an office-based setting, and the highest risk cases would tend to be treated in an HOPD (with ASCs somewhere in between). Indeed, a recent unpublished study confirms that patients undergoing surgery from HOPDs were more likely to have serious comorbid conditions and more likely to have been hospitalized or have an emergency department visit 1 year prior to the date of surgery, compared with patients undergoing surgery in physician offices.³⁷ Under this assumption, if the true quality of care is approximately equal across settings, we would expect the lowest (unadjusted) hospitalization rates to be for office-based sites and the highest (unadjusted) rates for HOPD. Furthermore, under these assumptions, with “perfect” risk adjustment (no nonignorable unobserved risk factors), the risk-adjusted hospitalization rates would be similar across settings (ie, if true quality is assumed to be equal).

The fact that the risk-adjusted rates were not found to be equal across settings suggests some combination of treatment quality heterogeneity or imperfect risk adjustment—risk-adjusted hospitalization rates consistently were higher in office and HOPD settings compared with ASCs.

Unfortunately, the results do not allow us to make much of an inference regarding HOPD vs ASC quality (ie, the higher HOPD rate could result from higher unmeasured risk for HOPD patients with equal quality, or inferior quality, or some elements of both). However, the adjusted rates are worse for office-based care vs ASC care, which (given the likely favorable selection into office-based care) cannot be dismissed as an artifact of imperfect risk adjustment. In other words, the fact that ASCs had lower risk-adjusted hospitalization rates compared with office-based sites, even though ASCs treated higher risk patients, implies that ASCs on average provide a higher quality of care than office-based settings.

Summary

Our findings update and expand on, but generally confirm, the findings reported in the Fleischer et al²⁵ study using Medicare claims data. For the 88 relatively complex outpatient surgical procedures included in our study, the risk-adjusted rate of hospitalization generally was higher for patients undergoing procedures at a physician’s office compared with those treated at an ASC, for both 7-day and 30-day postprocedure hospitalization measures. This pattern was most consistent for higher complexity procedures, consistent with theory. Risk-adjusted hospitalization rates also generally were higher for HOPDs compared with ASCs, but that result may be an artifact of unmeasured risk factors not accounted for in our risk adjustment model.

Conclusions

Using a rich data set of more than 1 million private health insurance claims in Florida from 2008 to 2012, we found high rates of change in setting from ASCs and HOPDs to physician offices for some of the study procedures, but low rates of change for many other procedures. This suggests that the observed high rate of growth in office-based outpatient procedures overall is dominated by growth in relatively low-complexity procedures not included in our study. For the more complex procedures included in our analysis, we found that risk-adjusted rates of hospitalizations following procedures in physician offices were significantly higher compared with ASCs for many of the procedures studied. These findings do not necessarily imply that office-based surgery universally results in poor outcomes but do suggest a need for ongoing research on the safety and efficacy of office-based surgery to facilitate guidance for determining, given patient severity, specific outpatient procedures that are appropriate for the less-intensive office-based setting and specific procedures that should ideally remain in the relatively more intensive ASC and hospital outpatient settings.

Appendix 1

Table A1.

Descriptions of 88 procedures selected for analysis.

CPT	Procedure description
14040	Adjacent tissue transfer or rearrangement, forehead, cheeks, chin, mouth, neck, axillae, genitalia, hands, and/or feet
14060	Adjacent tissue transfer or rearrangement, eyelids, nose, ears, and/or lips; defect 10 cm2 or less
15823	Blepharoplasty, upper eyelid; with excessive skin weighting down lid
17311	Mohs micrographic technique, including removal of all gross tumor, surgical excision of tissue specimens, mapping, color coding of specimens, microscopic examination of specimens by the surgeon, and histopathologic preparation including routine stain(s)
19120	Excision of cyst, fibroadenoma, or other benign or malignant tumor, aberrant breast tissue, duct lesion, nipple or areolar lesion (except 19300), open, men or women, 1 or more lesions
19125	Excision of breast lesion identified by preoperative placement of radiological marker, open; single lesion
19301	Mastectomy, partial (eg, lumpectomy, tylectomy, quadrantectomy, segmentectomy)
19318	Reduction mammaplasty
19350	Nipple/areola reconstruction
19380	Revision of reconstructed breast
20680	Removal of implant; deep
20926	Tissue grafts, other
21930	Excision, tumor, soft tissue of back or flank, subcutaneous; less than 3 cm
22851	Application of intervertebral biomechanical device(s)
26116	Excision, tumor, soft tissue, or vascular malformation, of hand or finger, subfascial (eg, intramuscular); less than 1.5 cm
27194	Closed treatment of pelvic ring fracture, dislocation, diastasis, or subluxation; with manipulation, requiring more than local anesthesia
28080	Excision, interdigital (Morton) neuroma, single, each
28090	Excision of lesion, tendon, tendon sheath, or capsule (including synovectomy); foot
28119	Ostectomy, calcaneus; for spur, with or without plantar fascial release
28122	Partial excision (craterization, saucerization, sequestrectomy, or diaphysectomy) bone; tarsal or metatarsal bone, except talus or calcaneus
28124	Partial excision (craterization, saucerization, sequestrectomy, or diaphysectomy) bone; phalanx of toe
28270	Capsulotomy; metatarsophalangeal joint, with or without tenorrhaphy, each joint (separate procedure)
28285	Correction, hammertoe
28289	Hallux rigidus correction with cheilectomy, debridement, and capsular release of the first metatarsophalangeal joint
28292	Correction, hallux valgus (bunion), with or without sesamoidectomy; Keller, McBride, or Mayo type procedure
28296	Correction, hallux valgus (bunion), with or without sesamoidectomy; with metatarsal osteotomy
28299	Correction, hallux valgus (bunion), with or without sesamoidectomy; by double osteotomy
28308	Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; other than first metatarsal, each
29822	Arthroscopy, shoulder, surgical; debridement, limited
29823	Arthroscopy, shoulder, surgical; debridement, extensive
29824	Arthroscopy, shoulder, surgical; distal claviculectomy including distal articular surface (Mumford procedure)
29827	Arthroscopy, shoulder, surgical; with rotator cuff repair
29875	Arthroscopy, knee, surgical; synovectomy, limited (eg, plica or shelf resection) (separate procedure)
29876	Arthroscopy, knee, surgical; synovectomy, major, 2 or more compartments
29877	Arthroscopy, knee, surgical; debridement/shaving of articular cartilage (chondroplasty)
29879	Arthroscopy, knee, surgical; abrasion arthroplasty (including chondroplasty if necessary) or multiple drilling/microfracture
29880	Arthroscopy, knee, surgical; with meniscectomy (medial and lateral, including any meniscal shaving) including debridement/shaving of articular cartilage (chondroplasty), same or separate compartment(s), when performed
29881	Arthroscopy, knee, surgical; with meniscectomy (medial or lateral, including any meniscal shaving) including debridement/shaving of articular cartilage (chondroplasty), same or separate compartment(s), when performed
29888	Arthroscopically aided anterior cruciate ligament repair/augmentation or reconstruction
30520	Septoplasty or submucous resection, with or without cartilage scoring, contouring or replacement with graft
31254	Nasal/sinus endoscopy, surgical; with ethmoidectomy, partial (anterior)
31255	Nasal/sinus endoscopy, surgical; with ethmoidectomy, total (anterior and posterior)
31267	Nasal/sinus endoscopy, surgical, with maxillary antrostomy; with removal of tissue from maxillary sinus
31276	Nasal/sinus endoscopy, surgical with frontal sinus exploration, with or without removal of tissue from frontal sinus
31288	Nasal/sinus endoscopy, surgical, with sphenoidotomy; with removal of tissue from the sphenoid sinus
36475	Endovenous ablation therapy of incompetent vein, extremity, inclusive of all imaging guidance and monitoring, percutaneous, radiofrequency; first vein treated
36561	Insertion of tunneled centrally inserted central venous access device, with subcutaneous port; age: 5 y or older
38525	Biopsy or excision of lymph node(s); open, deep axillary node(s)
42820	Tonsillectomy and adenoidectomy; younger than 12 y of age
43770	Laparoscopy, surgical, gastric restrictive procedure; placement of adjustable gastric restrictive device
45380	Colonoscopy, flexible, proximal to splenic flexure; with biopsy, single or multiple
45381	Colonoscopy, flexible, proximal to splenic flexure; with directed submucosal injection(s), any substance
45383	Colonoscopy, flexible, proximal to splenic flexure; with ablation of tumor(s), polyp(s), or other lesion(s) not amenable to removal by hot biopsy forceps, bipolar cautery, or snare technique
45384	Colonoscopy, flexible, proximal to splenic flexure; with removal of tumor(s), polyp(s), or other lesion(s) by hot biopsy forceps or bipolar cautery
45385	Colonoscopy, flexible, proximal to splenic flexure; with removal of tumor, polyp, or other lesion by snare technique
46260	Hemorrhoidectomy, internal and external, 2 or more columns/groups
47562	Laparoscopy, surgical; cholecystectomy
47563	Laparoscopy, surgical; cholecystectomy with cholangiography
49320	Laparoscopy, abdomen, peritoneum, and omentum, diagnostic, with or without collection of specimen(s) by brushing or washing (separate procedure)
49505	Repair initial inguinal hernia, age: 5 y or older; reducible
49560	Repair initial incisional or ventral hernia; reducible
49568	Implantation of mesh or other prosthesis for open incisional or ventral hernia repair or mesh for closure of debridement for necrotizing soft tissue infection (list separately in addition to code for the incisional or ventral hernia repair)
49585	Repair umbilical hernia, age: 5 y or older; reducible
50590	Lithotripsy, extracorporeal shock wave
52353	Cystourethroscopy, with ureteroscopy and/or pyeloscopy; with lithotripsy (ureteral catheterization is included)
57288	Sling operation for stress incontinence
57520	Conization of cervix, with or without fulguration, with or without dilation and curettage, with or without repair; cold knife or laser
58345	Transcervical introduction of fallopian tube catheter for diagnosis and/or re-establishing patency (any method), with or without hysterosalpingography
58558	Hysteroscopy, surgical; with sampling (biopsy) of endometrium and/or polypectomy, with or without D and C
58561	Hysteroscopy, surgical; with removal of leiomyomata
58563	Hysteroscopy, surgical; with endometrial ablation
58565	Hysteroscopy, surgical; with bilateral fallopian tube cannulation to induce occlusion by placement of permanent implants
58660	Laparoscopy, surgical; with lysis of adhesions (salpingolysis, ovariolysis) (separate procedure)
58661	Laparoscopy, surgical; with removal of adnexal structures (partial or total oophorectomy and/or salpingectomy)
58662	Laparoscopy, surgical; with fulguration or excision of lesions of the ovary, pelvic viscera, or peritoneal surface by any method
58670	Laparoscopy, surgical; with fulguration of oviducts (with or without transection)
59820	Treatment of missed abortion, completed surgically; first trimester
63030	Laminotomy (hemilaminectomy), with decompression of nerve root(s), including partial facetectomy, foraminotomy, and/or excision of herniated intervertebral disc; 1 interspace, lumbar
63650	Percutaneous implantation of neurostimulator electrode array, epidural
64704	Neuroplasty; nerve of hand or foot
64721	Neuroplasty and/or transposition; median nerve at carpal tunnel
65426	Excision or transposition of pterygium; with graft
66982	Extracapsular cataract removal with insertion of intraocular lens prosthesis (1-stage procedure), manual or mechanical technique, complex, requiring devices or techniques not generally used in routine
66984	Extracapsular cataract removal with insertion of intraocular lens prosthesis (1-stage procedure), manual or mechanical technique
67210	Destruction of localized lesion of retina, 1 or more sessions; photocoagulation
67904	Repair of blepharoptosis; (tarso) levator resection or advancement, external approach
69610	Tympanic membrane repair, with or without site preparation of perforation for closure, with or without patch
69620	Myringoplasty (surgery confined to drumhead and donor area)

Current Procedural Terminology (CPT) 2014, American Medical Association.

Table A2.

Proportion of procedures performed in physician offices, 2008-2012.

CPT	Short description	Work RVU	Total number of surgeries (2008–2012)	Proportion of procedures in office (2008–2012), %
43770	Lap. place gastr. adj. device	18.00	15 117	1.7
19318	Reduction of large breast	16.03	10 371	2.8
29827	Arthroscopy rotator cuff repr	15.59	27 842	0.6
29888	Knee arthroscopy/surgery	14.30	32 415	0.6
63030	Low back disk surgery	13.18	17 487	0.7
58662	Laparoscopy excise lesions	12.15	29 258	0.8
57288	Repair bladder defect	12.13	24 484	1.4
49560	Rpr ventral hern. init. reduc.	11.92	12 986	0.9
58660	Laparoscopy lysis	11.59	9821	1.5
28299	Correction of bunion	11.57	5976	2.0
47563	Lap. cholecystectomy/graph	11.47	41 094	0.5
58661	Laparoscopy removal of adnexa	11.35	18 926	1.1
66982	Cataract surgery complex	11.08	7518	2.0
47562	Laparoscopic cholecystectomy	10.47	65 363	0.6
19380	Revise breast reconstruction	10.41	7952	2.7
27194	Treat pelvic ring fracture	10.20	2898	11.1
19301	Partial mastectomy	10.13	14 420	0.9
58561	Hysteroscopy remove myoma	9.99	5121	3.1
50590	Fragmenting of kidney stone	9.77	38 102	1.7
14060	Adjacent tissue transfer; face; 10 sq cm or less	9.23	14 537	56.4
19350	Breast reconstruction	9.11	6412	12.0
28292	Correction of bunion	9.05	5293	3.1
29879	Knee arthroscopy/surgery	8.99	24 213	0.5
29824	Shoulder arthroscopy/surgery	8.98	27 867	0.5
29876	Knee arthroscopy/surgery	8.87	21 406	0.5
31276	Sinus endoscopy surgical	8.84	17 486	0.9
14040	Adjacent tissue transfer; 10 sq cm or less	8.60	15 099	47.2
66984	Cataract surg. with iol. 1 stage	8.52	133 934	4.7
29823	Shoulder arthroscopy/surgery	8.36	20 162	0.5
28296	Correction of bunion	8.35	26 453	1.9
28289	Repair hallux rigidus	8.31	4954	2.3
29877	Knee arthroscopy/surgery	8.30	52 496	0.5
67904	Repair eyelid defect	7.97	4728	9.9
49505	Inguinal hernia repair; age 5+	7.96	33 005	0.6
2982	Shoulder arthroscopy/surgery	7.60	18 929	0.5
52353	Cystouretero. with lithotripsy	7.50	17 556	0.6
29880	Knee arthroscopy/surgery	7.39	41 496	0.6
63650	Implant neuroelectrodes	7.15	7369	25.6
58565	Hysteroscopy sterilization	7.12	12 610	71.8
29881	Knee arthroscopy/surgery	7.03	104 970	0.5
30520	Repair of nasal septum	7.01	51 196	1.1
31255	Removal of ethmoid sinus	6.95	28 943	0.9
15823	Revision of upper eyelid	6.81	9458	14.1
28122	Partial removal of foot bone	6.76	3862	4.2
26116	Exc. hand tum. deep <1.5 cm	6.74	4194	2.7
46260	Remove in./ex. hem. groups 2+	6.73	6924	2.0
36475	Endovenous rf. first vein	6.72	23 041	86.8
22851	Apply spine prosth. device	6.70	5105	2.7
19125	Excision breast lesion	6.69	15 333	1.2
49585	Rpr umbil. hern. reduc. >5 y	6.59	19 615	0.7
29875	Knee arthroscopy/surgery	6.45	23 176	0.6
38525	Biopsy/removal lymph nodes	6.43	13 747	0.9
67210	Treatment of retinal lesion	6.36	20 353	89.7
17311	Mohs 1 stage h/n/hf/g	6.20	54 971	92.5
58563	Hysteroscopy ablation	6.16	52 172	31.0
65426	Removal of eye lesion	6.05	5908	7.3
36561	Insert tunneled cv. cath.	6.04	28 079	2.2
69620	Repair of eardrum	6.03	3043	4.4
20680	Removal of support implant	5.96	30 992	10.4
19120	Removal of breast lesion	5.92	22 216	4.4
58670	Laparoscopy tubal cautery	5.91	11 441	0.8
45383	Lesion removal colonoscopy	5.86	26 849	3.1
20926	Removal of tissue for graft	5.79	12 763	10.5
28285	Repair of hammertoe	5.62	22 361	5.7
28119	Removal of heel spur	5.56	4713	2.5
28308	Incision of metatarsal	5.48	8049	2.7
31267	Endoscopy maxillary sinus	5.45	27 311	0.9
45385	Lesion removal colonoscopy	5.30	253 966	2.2
49320	Diag. laparo. separate proc.	5.14	14 329	1.3
28124	Partial removal of toe	5.00	4798	26.1
64721	Carpal tunnel surgery	4.97	36 249	1.2
21930	Exc. back les. sc. <3 cm	4.94	6103	27.5
28270	Release of foot contracture	4.93	6371	8.7
49568	Hernia repair with mesh	4.88	17 347	0.6
28080	Removal of foot lesion	4.86	7854	4.3
59820	Care of miscarriage	4.84	30 499	3.2
58558	Hysteroscopy biopsy	4.74	69 647	19.6
58345	Reopen fallopian tube	4.70	2826	10.9
45384	Lesion remove colonoscopy	4.69	80 404	1.5
64704	Revise hand/foot nerve	4.69	2869	4.0
31254	Revision of ethmoid sinus	4.64	9127	0.9
31288	Nasal/sinus endoscopy surg.	4.57	8905	1.1
28090	Removal of foot lesion	4.55	4131	8.9
69610	Repair of eardrum	4.47	5089	20.1
45380	Colonoscopy and biopsy	4.43	487 571	1.4
42820	Remove tonsils and adenoids	4.22	48 730	0.4
45381	Colonoscopy submucous inj.	4.19	18 866	0.9
57520	Conization of cervix	4.11	6394	5.5
Total		N/A	2 382 127	7.3

Table A3.

Risk-adjusted hospital admission rates within 7 and 30 days after the procedure, 71 procedure models with risk adjustment.

CPT	Short description	Office		ASC		HOPD
		7-day	30-day	7-day	30-day	7-day	30-day
14040	Adjacent tissue transfer; 10 sq cm or less	0.23%	0.91%	0.21%	0.88%	1.32%a	2.34%a
15823	Revision of upper eyelid	0.21%	0.58%	0.07%	0.41%	0.18%	0.53%
17311	Mohs 1 stage h/n/hf/g	0.19%	0.73%	0.23%	0.77%	0.40%a	1.16%a
19120	Removal of breast lesion	0.63%	2.69%	0.20%a	1.55%a	0.71%	2.25%
19301	Partial mastectomy	0.84%	3.96%	0.51%	2.57%	1.32%	3.69%
19318	Reduction of large breast	3.99%	5.99%	0.83%a	1.43%a	4.37%	5.35%
19350	Breast reconstruction	0.76%	1.52%	0.24%	0.72%	2.34%a	3.42%a
19380	Revise breast reconstruction	0.85%	1.29%	0.31%	1.73%	2.29%	3.49%
20680	Removal of support implant	0.80%	1.41%	0.43%a	1.31%	3.26%a	4.26%a
20926	Removal of tissue for graft	2.87%	3.30%	1.41%a	2.08%	6.35%a	7.22%a
21930	Exc. back les. sc. <3 cm	0.27%	0.62%	0.13%	0.63%	0.65%	1.04%
22851	Apply spine prosth. device	78.70%	78.50%	6.59%a	7.28%a	33.10%a	33.80%a
27194	Treat pelvic ring fracture	0.69%	0.43%	0.66%	1.03%	1.37%	1.71%
28090	Removal of foot lesion	0.34%	1.05%	0.36%	0.69%	0.33%	0.80%
28122	Partial removal of foot bone	2.78%	6.54%	0.75%a	1.76%a	2.14%	3.60%a
28124	Partial removal of toe	0.34%	0.92%	0.55%	0.89%	0.72%	1.71%
28270	Release of foot contracture	0.36%	0.74%	0.50%	1.07%	1.19%	2.01%a
28285	Repair of hammertoe	0.14%	0.73%	0.32%	0.98%	0.73%a	1.33%
28292	Correction of bunion	0.71%	1.39%	0.29%	0.52%	0.50%	0.93%
28296	Correction of bunion	0.41%	1.46%	0.13%	0.59%a	0.32%	0.77%
29822	Shoulder arthroscopy/surgery	3.57%	3.53%	0.55%a	0.92%a	1.10%a	1.63%
29823	Shoulder arthroscopy/surgery	3.51%	4.47%	0.40%a	0.94%a	0.92%a	1.43%a
29824	Shoulder arthroscopy/surgery	3.38%	4.08%	0.35%a	0.78%a	0.99%a	1.51%a
29827	Arthroscopy rotator cuff repr.	1.81%	2.41%	0.59%	1.04%	1.01%	1.46%
29876	Knee arthroscopy/surgery	4.51%	5.55%	0.46%a	1.18%a	0.94%a	1.67%a
29877	Knee arthroscopy/surgery	0.37%	1.43%	0.41%	1.07%	0.65%	1.40%
29879	Knee arthroscopy/surgery	1.74%	1.71%	0.32%a	1.06%	0.65%	1.47%
29881	Knee arthroscopy/surgery	0.69%	1.04%	0.35%	0.90%	0.49%	1.13%
29888	Knee arthroscopy/surgery	1.67%	2.21%	0.56%	1.24%	1.34%	1.94%
30520	Repair of nasal septum	2.88%	3.10%	0.34%a	0.79%a	1.54%a	2.07%
31254	Revision of ethmoid sinus	2.75%	2.53%	0.39%a	0.98%	1.08%	1.98%
31255	Removal of ethmoid sinus	1.21%	1.62%	0.45%	1.07%	1.19%	1.95%
31267	Endoscopy maxillary sinus	1.25%	1.21%	0.42%	1.08%	1.05%	1.87%
31276	Sinus endoscopy surgical	2.00%	2.14%	0.55%a	1.11%	1.23%	2.00%
31288	Nasal/sinus endoscopy surg.	1.34%	1.46%	0.69%	1.28%	1.46%	2.42%
36561	Insert tunneled cv cath.	2.17%	10.80%	3.54%	11.30%	4.93%a	13.10%
38525	Biopsy/removal lymph nodes	19.90%	22.30%	6.89%a	14.90%a	8.49%a	12.50%a
43770	Lap. place gastr. adj. device	7.50%	7.55%	1.15%a	1.88%a	7.37%	8.05%
45380	Colonoscopy and biopsy	0.70%	2.24%	0.59%	2.05%	0.73%	2.34%
45381	Colonoscopy submucosa inject.	1.27%	10.60%	3.62%	12.20%	4.12%	12.20%
45383	Lesion removal colonoscopy	0.76%	1.93%	0.73%	1.95%	0.60%	1.73%
45384	Lesion removal colonoscopy	0.48%	1.71%	0.65%	1.80%	0.70%	2.01%
45385	Lesion removal colonoscopy	0.58%	1.74%	0.69%	2.11%	0.78%	2.31%a
46260	Remove in./ex. hem groups 2+	1.40%	2.10%	1.99%	2.79%	3.60%	4.85%
47562	Laparoscopic cholecystectomy	9.81%	11.30%	1.68%a	2.63%a	4.75%a	5.86%a
47563	Laparo cholecystectomy/graph	14.40%	16.00%	1.95%a	2.95%a	5.83%a	6.81%a
49320	Diag. laparo. separate proc.	14.10%	15.20%	1.71%a	4.64%a	7.10%a	10.30%a
49560	Rpr ventral hern. init. reduc.	13.10%	14.90%	1.18%a	1.88%a	12.50%	13.80%
49568	Hernia repair with mesh	12.70%	12.60%	1.36%a	2.36%a	12.20%	13.50%
49585	Rpr umbil. hern. reduc. >5 y	7.63%	9.16%	0.75%a	1.20%a	3.34%a	4.12%a
50590	Fragmenting of kidney stone	2.95%	5.16%	1.96%	3.64%	2.16%	3.92%
52353	Cystouretero with lithotripsy	8.16%	10.00%	2.32%a	4.01%a	3.82%a	5.92%
57288	Repair bladder defect	35.30%	36.40%	0.59%a	1.15%a	12.10%a	12.80%a
57520	Conization of cervix	2.34%	3.48%	1.16%	3.07%	2.67%	4.44%
58558	Hysteroscopy biopsy	0.50%	2.78%	0.38%	2.25%a	0.98%a	2.91%
58561	Hysteroscopy removal myoma	3.78%	3.89%	0.39%a	1.22%a	1.21%a	2.34%
58563	Hysteroscopy ablation	0.45%	1.09%	0.45%	1.14%	0.75%a	1.57%a
58660	Laparoscopy lysis	14.50%	15.30%	1.79%a	3.29%a	6.23%a	7.81%a
58661	Laparoscopy removal adnexa	10.60%	11.70%	0.99%a	1.97%a	5.10%a	6.10%a
58662	Laparoscopy excise lesions	4.42%	5.22%	0.88%a	1.52%a	2.28%a	3.10%
58670	Laparoscopy tubal cautery	2.80%	4.10%	0.43%a	0.95%a	1.04%	1.54%a
59820	Care of miscarriage	0.69%	0.80%	0.54%	0.88%	1.45%	1.81%a
63650	Implant neuroelectrodes	0.51%	4.55%	0.59%	4.80%	1.59%a	5.21%
64704	Revise hand/foot nerve	1.09%	0.80%	0.58%	1.22%	0.97%	1.59%
64721	Carpal tunnel surgery	0.47%	1.12%	0.18%	0.75%	0.63%	1.50%
66982	Cataract surgery complex	0.67%	1.89%	0.37%	1.25%	0.38%	1.30%
66984	Cataract surg. with iol. 1 stage	0.26%	0.88%	0.19%	0.98%	0.20%	1.06%
67210	Treatment of retinal lesion	0.56%	2.35%	0.54%	2.67%	2.05%a	4.92%a
67904	Repair eyelid defect	0.55%	0.86%	0.13%a	0.63%	0.26%	0.78%
69610	Repair of eardrum	0.51%	1.14%	0.08%	0.16%a	0.29%	0.34%a
69620	Repair of eardrum	0.29%	0.54%	0.13%	0.12%	0.51%	0.72%
All 71 procedures		1.62%	2.82%	0.86%a	2.14%a	1.75%a	3.09%a

Abbreviations: ASC, ambulatory surgery center; CPT, Current Procedure Terminology; HOPD, hospital outpatient department.

Authors’ analysis of Truven MarketScan commercial claims data; see text for description.

^aDifference between office setting rates and rates of others settings statistically significant at P ⩽ .05. Based on 71 procedures for which risk adjustment regressions converged. Ranked from highest work RVU to lowest work RVU.

Table A4.

Full regressions of hospital admissions within 7 and 30 days after procedure on main sample.

	7-day			30-day
	OR	P > z	95% CI	OR	P > z	95% CI
Place of service
Office (reference)
Outpatient hospital	1.09	.041	1.00–1.18	1.10	.001	1.04–1.16
ASC	0.51	0	0.46–0.55	0.73	0	0.69–0.78
Age group
<35 (reference)
35-44	1.17	0	1.13–1.23	1.26	0	1.22–1.31
45-54	1.18	0	1.13–1.23	1.26	0	1.22–1.30
55-64	1.24	0	0.22–0.22	1.00	0	0.22–0.22
Female	1.04	.027	1.00–1.07	1.02	.116	1.00–1.05
Year
2008 (reference)
2009	0.93	0	0.89–0.96	0.96	.004	0.93–0.99
2010	0.84	0	0.81–0.87	0.89	0	0.86–0.92
2011	0.81	0	0.78–0.84	0.87	0	0.85–0.90
2012	0.81	0	0.77–0.84	0.85	0	0.82–0.88
Employment status
Active (full-time or part-time)
Retiree, dependents, COBRA continuee, or long-term disability	1.13	0	1.06–1.20	1.12	0	1.07–1.18
Other/unknown	0.99	.403	0.96–1.02	1.03	.004	1.01–1.06
CMS-HCC score	1.78	0	1.67–1.90	2.28	0	2.17–2.39
CPT code
14040 (reference)
14060	0.50	0	0.35–0.70	0.53	0	0.42–0.66
15823	0.14	0	0.06–0.30	0.26	0	0.17–0.41
17311	0.26	0	0.20–0.34	0.49	0	0.41–0.57
19120	0.84	.178	0.64–1.08	1.47	0	1.23–1.75
19125	0.55	0	0.40–0.75	1.26	.015	1.05–1.52
19301	1.53	.001	1.19–1.97	2.21	0	1.86–2.63
19318	5.31	0	4.26–6.63	3.34	0	2.81–3.96
19350	2.36	0	1.80–3.09	1.85	0	1.50–2.29
19380	2.46	0	1.91–3.17	2.03	0	1.67–2.46
20680	2.57	0	2.00–3.30	1.77	0	1.47–2.13
20926	7.52	0	5.93–9.55	4.43	0	3.71–5.30
21930	0.51	.003	0.33–0.79	0.56	0	0.41–0.76
22851	53.26	0	41.40–68.52	29.04	0	24.10–34.99
26116	0.18	0	0.07–0.46	0.47	.001	0.31–0.73
27194	0.57	.371	0.17–1.94	0.84	.601	0.45–1.60
28080	0.33	.001	0.17–0.62	0.65	.013	0.46–0.91
28090	0.43	.007	0.23–0.79	0.49	.001	0.32–0.76
28119	0.44	.01	0.23–0.82	0.63	.018	0.43–0.92
28122	2.21	0	1.56–3.12	2.03	0	1.56–2.63
28124	0.70	.125	0.45–1.10	0.85	.301	0.63–1.16
28270	1.11	.578	0.77–1.61	1.01	.966	0.77–1.32
28285	0.70	.025	0.51–0.96	0.76	.014	0.61–0.95
28289	0.36	.001	0.20–0.67	0.47	0	0.32–0.71
28292	0.54	.014	0.33–0.88	0.51	0	0.35–0.74
28296	0.33	0	0.23–0.47	0.48	0	0.37–0.61
28299	0.76	.24	0.48–1.20	0.52	.001	0.36–0.75
28308	0.64	.045	0.42–0.99	0.66	.008	0.49–0.90
29822	1.22	.17	0.92–1.63	0.95	.633	0.76–1.18
29823	1.01	.958	0.75–1.35	0.86	.197	0.69–1.08
29824	1.02	.867	0.77–1.36	0.85	.117	0.68–1.04
29827	1.11	.447	0.84–1.48	0.86	.146	0.69–1.06
29875	0.64	.005	0.47–0.88	0.76	.013	0.61–0.94
29876	1.07	.632	0.80–1.44	1.05	.678	0.85–1.29
29877	0.74	.032	0.56–0.97	0.86	.135	0.71–1.05
29879	0.72	.034	0.53–0.97	0.90	.319	0.72–1.11
29880	0.70	.013	0.52–0.93	0.85	.107	0.69–1.04
29881	0.58	0	0.45–0.76	0.71	0	0.59–0.86
29888	1.59	.001	1.21–2.08	1.34	.004	1.10–1.64
30520	3.39	0	2.45–4.69	1.75	0	1.38–2.24
31254	2.43	0	1.64–3.59	1.70	0	1.27–2.28
31255	2.69	0	1.92–3.76	1.69	0	1.32–2.18
31267	2.41	0	1.71–3.37	1.65	0	1.28–2.13
31276	2.86	0	2.02–4.06	1.75	0	1.35–2.28
31288	3.39	0	2.33–4.92	2.09	0	1.58–2.77
36475	0.20	0	0.14–0.30	0.42	0	0.32–0.54
36561	4.17	0	3.35–5.20	5.79	0	4.96–6.77
38525	10.77	0	8.74–13.26	7.90	0	6.77–9.22
42820	5.86	0	4.24–8.10	2.67	0	2.10–3.41
43770	3.86	0	2.89–5.16	2.39	0	1.90–3.00
45380	0.90	.396	0.71–1.14	1.72	0	1.46–2.03
45381	5.31	0	4.14–6.80	10.28	0	8.66–12.21
45383	0.76	.064	0.57–1.02	1.28	.011	1.06–1.56
45384	0.85	.199	0.66–1.09	1.41	0	1.19–1.68
45385	0.99	.938	0.78–1.26	1.72	0	1.46–2.03
46260	3.48	0	2.65–4.56	2.93	0	2.39–3.60
47562	8.38	0	6.44–10.91	5.69	0	4.67–6.92
47563	10.43	0	8.00–13.60	6.67	0	5.47–8.14
49320	10.47	0	8.21–13.34	8.22	0	6.89–9.81
49505	1.25	.091	0.97–1.61	1.08	.444	0.89–1.30
49560	12.54	0	9.90–15.90	8.70	0	7.33–10.32
49568	12.13	0	9.59–15.36	8.49	0	7.17–10.06
49585	3.31	0	2.58–4.23	2.53	0	2.11–3.03
50590	3.12	0	2.36–4.11	2.36	0	1.91–2.92
52353	5.17	0	3.91–6.85	3.45	0	2.78–4.27
57288	19.68	0	15.39–25.15	9.23	0	7.70–11.06
57520	4.51	0	3.36–6.05	3.64	0	2.91–4.54
58345	0.32	.069	0.09–1.09	0.53	.053	0.27–1.01
58558	1.41	.008	1.10–1.82	2.31	0	1.93–2.77
58561	2.01	0	1.39–2.90	1.76	0	1.35–2.31
58563	1.09	.518	0.84–1.42	1.12	.261	0.92–1.35
58565	0.57	.019	0.35–0.91	0.59	.004	0.42–0.84
58660	10.40	0	8.06–13.40	6.50	0	5.36–7.86
58661	8.19	0	6.39–10.49	4.75	0	3.95–5.72
58662	3.86	0	2.99–4.98	2.52	0	2.08–3.05
58670	2.16	0	1.54–3.03	1.60	0	1.23–2.08
59820	1.15	.402	0.83–1.60	0.89	.427	0.68–1.18
63030	9.06	0	7.04–11.66	6.05	0	5.03–7.27
63650	1.48	.025	1.05–2.09	3.36	0	2.69–4.19
64704	0.88	.665	0.49–1.59	0.99	.96	0.67–1.46
64721	0.68	.028	0.48–0.96	0.88	.271	0.70–1.11
65426	0.09	0	0.03–0.34	0.19	0	0.10–0.37
66982	0.48	.033	0.25–0.94	0.71	.095	0.48–1.06
66984	0.26	0	0.16–0.43	0.55	0	0.40–0.76
67210	0.65	.117	0.38–1.12	1.06	.721	0.77–1.47
67904	0.25	.002	0.11–0.60	0.40	0	0.24–0.65
69610	0.68	.225	0.37–1.26	0.51	.004	0.32–0.80
69620	1.10	.786	0.54–2.26	0.61	.093	0.35–1.08
MDC
Missing/invalid diagnosis (reference)
Nervous	1.88	0	1.33–2.65	1.70	0	1.30–2.24
Eye	2.17	.004	1.28–3.69	2.23	0	1.54–3.21
Ear, nose, mouth, and throat	1.02	.91	0.71–1.47	1.29	.094	0.96–1.73
Respiratory	1.80	.001	1.27–2.54	1.44	.008	1.10–1.89
Circulatory	3.32	0	2.42–4.56	2.74	0	2.12–3.55
Digestive	2.49	0	1.90–3.27	1.84	0	1.46–2.32
Liver, pancreas	1.35	.049	1.00–1.83	1.18	.192	0.92–1.53
Musculoskeletal	2.16	0	1.59–2.95	1.86	0	1.44–2.40
Skin, breast	1.88	0	1.41–2.51	1.78	0	1.40–2.26
Metabolic	3.82	0	2.77–5.26	2.97	0	2.26–3.91
Kidney	1.84	0	1.38–2.45	2.03	0	1.59–2.59
Male reproductive	1.77	.015	1.12–2.79	1.66	.006	1.16–2.37
Female reproductive	1.44	.006	1.11–1.87	1.50	0	1.21–1.87
Pregnancy, childbirth	3.11	0	2.24–4.33	2.46	0	1.85–3.28
Blood	1.78	.002	1.24–2.54	2.57	0	1.97–3.34
Myeloproliferative diseases	2.51	0	1.86–3.38	2.15	0	1.68–2.74
Injuries, poisonings	3.14	0	2.21–4.47	2.64	0	1.96–3.54
Health status	1.39	.023	1.05–1.84	1.07	.58	0.85–1.35
Others	6.11	0	4.03–9.26	4.93	0	3.47–7.00
Cons	0.00	0	0.00–0.00	0.00	0	0.00–0.01

Abbreviations: ASC, ambulatory surgery center; CI, confidence interval; CMS-HCC, Centers for Medicare and Medicaid Services-Hierarchical Condition Category; CPT, Current Procedure Terminology; MDC, Major Diagnostic Category; OR, odds ratio.