Table 1.
Discovery and replication cohorts: descriptive information on KLF15 SNPs and genotype frequencies.
| SNPsa | Chromosome positionb | Gene region position | Major/minor alleles | Discovery cohort |
Replication cohort |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype frequencies, % (n) | MAF | Genotype frequencies, % (n) | MAF | ||||||||
| rs9838915 | 1.26E + 08 | Intron 2 | G/A | GG | GA | AA | 15 | GG | GA | AA | 18 |
| 74.0 (235) | 22.6 (72) | 3.4 (11) | 66.3 (3673) | 30.5 (1691) | 3.1 (174) | ||||||
| rs6796325 | 1.26E + 08 | Intron 2 | T/C | TT | TC | CC | 29 | TT | TC | CC | 23 |
| 52.0 (165) | 38.6 (123) | 9.4 (30) | 59.8 (3338) | 35.1 (1959) | 5.1 (285) | ||||||
MAF = minor allele frequency.
a
dbSNP rs identification numbers (http://www.ncbi.nlm.nih.gov/SNP/, last accessed 2nd August 2016).
b
Chromosome 3 SNP positions using the genomic contig NT_005612·17 (http://www.ncbi.nlm.nih.gov/nuccore/NT_005612.17, last accessed 2nd August 2016).