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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1990 Jun;87(11):4198–4201. doi: 10.1073/pnas.87.11.4198

Mitochondrial DNA evolution in experimental populations of Drosophila subobscura.

M Fos 1, M A Domínguez 1, A Latorre 1, A Moya 1
PMCID: PMC54075  PMID: 2349229

Abstract

When two mitochondrial DNA (mtDNA) haplotypes of Drosophila subobscura compete in experimental populations with discrete generations, one or the other approaches fixation, depending on the nuclear background with which they are associated. The approach to fixation, however, is strongly dependent on the effective number of females in the population, Nf. Whether or not the ultimate fate of a given mtDNA haplotype is determined by random genetic drift depends on Nf as well as on the relative fitnesses. Our experimental results show that the mtDNA polymorphisms observed in natural populations are affected by interactions among nuclear polymorphisms, random genetic drift, and direct selection on the mtDNA haplotypes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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