Table 3.
PBCV-1 antigenic variants that affect the molecular weight of the major capsid glycoprotein.
| Antisera Classes | Predicted MW (kDa) c | SDS-PAGE Estimates (kDa) d | |
|---|---|---|---|
| Class a | Label b | ||
| + | Wild-type | 54.1 | 54 |
| F | CME6 | 54 | not determined |
| A | P91 | 52.8 | 53 |
| E | EPA-15 | 52.8 | not determined |
| B | EPA-2 | 51.6 | 52 |
| C | E1L3 | 51.1 | 51 |
| D | P1L6 | 50.5 | 50.5 |
a Listed in order of predicted molecular weight based on nuclear magnetic resonance (NMR) analysis (De Castro et al., [44,45]); b representative mutant strain label; c the gene encoding the PBCV-1 major capsid protein (a430l) is wild-type in sequence and does not vary among antisera classes; d Graves et al. [46]. MW, molecular weight.