Appendix Table 1.

Analysis of post-treatment test characteristics for detection of CIN2+ based on complete case.^a

	Sensitivity	Specificity	Correctly Classified	PPV	NPV
VIA	0.31 (0.21, 0.40)	0.83 (0.79, 0.87)	0.61 (0.56, 0.65)	0.27 (0.19, 0.35)	0.85 (0.81, 0.89)
PAP	0.47 (0.39, 0.54)	0.93 (0.90, 0.96)	0.71 (0.67, 0.75)	0.56 (0.48, 0.65)	0.90 (0.86, 0.94)
HR HPV	0.86 (0.75, 0.97)	0.57 (0.52, 0.62)	0.50 (0.46, 0.55)	0.29 (0.24, 0.34)	0.95 (0.90, 1.00)
VIA & PAP	0.15 (0.10, 0.20)	0.97 (0.95, 1.00)	0.70 (0.66, 0.74)	0.53 (0.36, 0.69)	0.85 (0.82, 0.89)
VIA & HR HPV	0.25 (0.17, 0.33)	0.89 (0.85, 0.92)	0.64 (0.59, 0.68)	0.32 (0.22, 0.41)	0.85 (0.81, 0.89)
PAP & HR HPV	0.33 (0.26, 0.40)	0.94 (0.91, 0.97)	0.70 (0.66, 0.74)	0.54 (0.43, 0.64)	0.88 (0.84, 0.92)
VIA & PAP & HR HPV	0.11 (0.06, 0.15)	0.98 (0.96, 1.00)	0.70 (0.66, 0.74)	0.47 (0.28, 0.65)	0.85 (0.81, 0.89)
VIA | PAP	0.65 (0.55, 0.75)	0.77 (0.73, 0.82)	0.62 (0.57, 0.66)	0.37 (0.31, 0.43)	0.92 (0.88, 0.96)
VIA | HR HPV	0.92 (0.81, 1.00)	0.51 (0.46, 0.56)	0.47 (0.43, 0.52)	0.28 (0.23, 0.32)	0.97 (0.92, 1.00)
PAP | HR HPV	1.00 (0.89, 1.00)	0.55 (0.50, 0.59)	0.51 (0.47, 0.55)	0.31 (0.27, 0.36)	1.00 (0.95, 1.00)
VIA | PAP | HR HPV	1.00 (0.89, 1.00)	0.50 (0.45, 0.55)	0.48 (0.43, 0.52)	0.29 (0.25, 0.33)	1.00 (0.95, 1.00)

^aAnalysis assumed triple negatives are truly negatives but excludes those with otherwise missing histology