Table 1. Demographic, clinical and neuropsychological data of the subjects in this study.
| MDD-aMCI(n=12) | aMCI(n=13) | Controls(n=14) | PValue | |
|---|---|---|---|---|
| Age (y) | 69.5 ± 10.3 | 72.7 ± 8.5 | 64.7 ± 7.0 | 0.319c |
| Gender (M/F) | 5/7 | 5/8 | 4/10 | 0.764b |
| Education (y) | 11 (13-9.3) | 9 (10.5 - 3) | 10 (12-6) | 0.309a |
| MMSE/30 | 27.2 ± 1.7 | 21.9 ± 4.9 | 27 (29.3-27) | 0.041a* |
| MoCA/30 | 22.5 ± 3.3 | 17.9 ± 5.0 | 25.5 ± 5.7 | 0.014c* |
| AVLT-immediate recall (n) | 4.2 ± 2.1 | 3.6 ± 1.4 | 7.3 ± 1.7 | 0.024c* |
| AVLT-delayed recall (n) | 5 (7.0-4.3) | 2.9 ±3.3 | 9.9 ± 2.6 | 0.004a** |
| AVLT-recognition (n) | 7 (12.5-4.3) | 7.5 ±3.7 | 11.3 ± 2.4 | 0.089a |
| CDR (score) | 0.5 | 0.5 | 0 | - |
| CDT (score) | 3 (3.0-2.0) | 2 (2.5-1.5) | 3 (3.0-2.75) (7.0-4.3) | 0.031a* |
Mean ± standard deviation; Median and inter-quartile range [M (QU-QL)].
a k-independent samples nonparametric tests; b chi square test; c analysis of variance;
* P < 0.05, ** P < 0.01;
Abbreviations: MDD-aMCI, Major Depression Disorder and Amnestic Mild Cognitive Impairment; aMCI, Amnestic Mild Cognitive Impairment; n, number; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; AVLT, Auditory Verbal Learning Test (AVLT); CDR, Clinical Dementia Rating; CDT, Clock Drawing Test.