Table 3.
The influence on H. pylori susceptibility in relation of ATG16L1 SNP (rs2241880)
| Genotype |
H. pylori negative |
H. pylori positive |
OR (95%CI)a | p value |
|---|---|---|---|---|
| ATG16L1, rs2241880 | (%), n=77 | (%), n=206 | ||
| AA | 43 (56) | 99 (48) | 1.00 (Ref) | |
| AG | 21 (27) | 89 (43) | 1.83 (1.00–3.42) | 0.048 |
| GG | 13 (17) | 18 (9) | 0.53 (0.23–1.22) | 0.134 |
| AA | 43 (56) | 99 (48) | 1.00 (Ref) | |
| AG/GG | 34 (44) | 107 (52) | 1.32 (0.77–2.28) | 0.311 |
| AA/AG | 64 (83) | 188 (91) | 1.00 (Ref) | |
| GG | 13 (17) | 18 (9) | 0.40 (0.18–0.91) | 0.029 |
| A allele | 107 (69) | 287 (70) | 1.00 (Ref) | |
| G allele | 47 (31) | 125 (30) | 0.99 (0.66–1.48) | 0.967 |
OR, odds ratio; CI, confidence interval; Ref, reference.
a
Adjusted for age and sex in logistic regression model.