Table 2. Characterization of TNIK-amplified and -non-amplified cancer cell lines.
Cell line | Cancer type | aCGH score | Average copy number | Gene/CEP ratio | TNIK FISH | β-Catenin IHC |
---|---|---|---|---|---|---|
PAMC82 | GC | 1.4 | 10 | 3.2 | AMP | CM+ |
T47D | BC | 1.3 | 7.2 | 2.3 | AMP | CM+++ |
AZ521 | GC | −0.09 | 2 | 0.9 | Normal | CN++ |
Abbreviations: aCGH, array comparative genomic hybridization; AMP, amplification; CEP, chromosome 3 probe; FISH, fluorescence in situ hybridization; IHC, immunohistochemistry; TNIK, Traf2- and Nck-interacting kinase.