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. 2017 May 9;8(3):e00303-17. doi: 10.1128/mBio.00303-17

FIG 5 .

FIG 5 

Heme fractionation of chloroquine (CQ)-treated Dd2Dd2 and Dd2Dd2+C101F (clone 1). (A to C) Amounts of (A) hemoglobin Fe (femtograms per cell), (B) free heme Fe (femtograms per cell), and (C) hemozoin Fe (femtograms per cell) present in Dd2Dd2 treated with increasing concentrations of CQ (used at multiples of the Dd2Dd2 CQ IC50). (D to F) Amounts of (D) hemoglobin Fe, (E) free heme Fe, and (F) hemozoin Fe present in Dd2Dd2+C101F parasites treated with multiples of their CQ IC50. Data (calculated from 6 to 8 values per concentration) are presented and statistically analyzed as per Fig. 4.