Erratum to: Purinergic Signalling
DOI 10.1007/s11302-016-9554-z
1. On page 2, in the last sentence of the first paragraph under the subheading “Animals groups”, “0.25 mL/Kg” should be “0.25 ml/Kg”.
2. On page 4, under the subheading “Statistical analysis”, “SE” should be “SEM”.
3. On page 7, under “Discussion” section, the paragraph that reads:
“P2X3 receptors are present mainly in small- to mediumsized neurons in the DRG. Selective distribution in small primary afferent neurons suggests a contributing role of the P2X3 receptor in nociception and pain [42]. Activation of the P2X3 receptor contributes to pain and hyperalgesia [43]. This study showed that the up-regulated expression of the P2X3 receptor was followed by an enhancement of mechanical and thermal hyperalgesia, resulting in the subsequent activation of the P2X3 receptor in the T2DM DRG. Cytokines liberated in the setting of peripheral inflammation contribute to pain. Thus, NONRATT021972 siRNA treatment could reduce the serum levels of TNF-α in T2DM rats, decrease the up-regulated expression of the P2X3 receptor in DRG, and relieve P2X3 receptor-mediated DNP in T2DM rats. This finding further confirmed that NONRATT021972 might be involved in the pathological process of T2DM”.
should be corrected to:
“P2X3 receptors are present mainly in small- to mediumsized neurons in the DRG. Selective distribution in small primary afferent neurons suggests a contributing role of the P2X3 receptor in nociception and pain [42]. Activation of the P2X3 receptor contributes to pain and hyperalgesia [43]. This study showed that the up-regulated expression of the P2X3 receptor was followed by an enhancement of mechanical and thermal hyperalgesia, resulting in the subsequent activation of the P2X3 receptor in the T2DM DRG. Thus, sinomenine treatment could decrease the up-regulated expression of the P2X3 receptor in DRG, and relieve P2X3 receptor-mediated DNP in T2DM rats”.
Footnotes
The online version of the original article can be found at 10.1007/s11302-016-9554-z