Table 2. Significant (p<0.05, corrected) Preferential Neural Responses to Negative Social Feedback (Negative Social Feedback>Positive Social Feedback) Under Each Drug Condition.
Brain region | MNI coordinates X, Y, Z | Cluster size | Peak T-value | Cluster corrected p-value |
---|---|---|---|---|
Placebo | ||||
Right anterior insula | 45, 26, −2 | 303 | 6.11 | <0.001 |
SMA incl. | 9, 5, 70 | 211 | 5.21 | 0.001 |
Pre-SMA | 3, 23, 58 | 4.60 | ||
Right fusiform/ITG | 48, −19, −17 | 102 | 5.86 | 0.028 |
Right TPJ/pSTS | 57, −55, 31 | 186 | 5.02 | 0.002 |
Right TPJ/pSTS | −57, −58, 28 | 133 | 4.37 | 0.011 |
Oxytocin | ||||
No significant activation | ||||
Vasopressin | ||||
No significant activation |
Abbreviations: ITG, inferior temporal gyrus; pSTS, posterior superior temporal sulcus; SMA, supplementary motor area; TPJ, temporoparietal junction.