Table 2.

Distribution of pneumonia events and incidence rates

Treatment	Events	Years in study	Incidence rate	Incident rate ratio (95% CI)	p value
(A)
No ICS	383	6885	0.056		Reference
ICS	738	10,836	0.068	1.22 (1.08, 1.38)	0.012
(B)
FP	437	5685	0.077	1.38 (1.20, 1.58)	<0.001
Other ICS	301	5151	0.058	1.05	0.52
No ICS	383	6885	0.056		Reference
(C)
FP/Plac	220	2720	0.081	1.45 (1.19, 1.77)	<0.001
FP/tio	217	2964	0.073	1.31 (1.08, 1.60)	0.006
Other ICS/plac	153	2461	0.062	1.12 (0.90, 1.38)	0.29
Other ICS/tio	148	2690	0.055	0.99 (0.79, 1.23)	0.94
No ICS/plac	184	3317	0.055		Reference
No ICS/tio	199	3567	0.056	1.00 (0.82, 1.22)	0.95

ICS Inhaled corticosteroids, FP fluticasone propionate, tio tiotropium, plac placebo