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. 2016 Oct 26;42(6):1305–1314. doi: 10.1038/npp.2016.216

Figure 3.

Figure 3

During a 6 h sleep deprivation (SD), Taar1 OE mice had more wakefulness (a) and decreased NREM sleep time (b) compared with Taar1 KO mice; REM sleep (c) did not differ across strains. The average wake bout duration during the SD was longer in Taar1 OE mice (d). Taar1 KO mice had more wake bouts during SD, whereas Taar1 OE mice had more wake bouts during recovery (e). Although recovery sleep time was unaffected by genotype (b), normalized NREM delta power during the first hour of recovery was increased in Taar1 OE mice compared with Taar1 KO and WT mice (f). N=5 KO, 7 OE, and 10 WT mice; *p<0.05 vs Taar1 KO mice, **p<0.05 vs WT and Taar1 KO mice.