Table 4.
Correlation of Clinicopathological Characteristics with Expression of UCH-L1 and α-internexin.
| Clinicopathological Features | Expression of UCH-L1 and α-internexin | P value | |
|---|---|---|---|
| Present (%) | Absent (%) | ||
| Patients with PNETs (n = 283) | 79 (27.9) | 204 (72.1) | |
| age at diagnosis (year) (n = 283) | 44.0 (19–79) | 51.0 (16–85) | 0.001 |
| gender (n = 283) | |||
| Male | 32 (26.7) | 88 (73.3) | 0.688 |
| Female | 47 (28.8) | 116 (71.2) | |
| grade (n = 243) | |||
| G1 | 34 (24.8) | 103 (75.2) | 0.331 |
| G2 | 27 (27.0) | 73 (73.0) | |
| G3 | 0 (0) | 6 (100) | |
| stage (n = 283) | |||
| I | 36 (41.4) | 51 (58.6) | 9.26 × 10−5 |
| II a | 31 (34.8) | 58 (65.2) | |
| II b | 5 (15.6) | 27 (84.4) | |
| III | 4 (13.3) | 26 (86.7) | |
| IV | 3 (6.7) | 42 (93.3) | |
| recurrence (n = 229) | |||
| No | 57 (34.5) | 108 (65.5) | 4.53 × 10−6 |
| Yes | 4 (6.3) | 59 (93.7) | |
| overall survival (n = 192) | 59 (30.7) | 133 (69.3) | 7.79 × 10−5 |
| death (n = 38) | 1 (2.6) | 37 (97.4) | |
| disease free survival (n = 163) | 57 (35.0) | 106 (65.0) | 6.10 × 10−7 |
| survival with disease or death (n = 65) | 3 (4.6) | 62 (95.4) | |
| All PNETs (n = 290) | |||
| location (n = 271) | 79 (27.2) | 211 (72.8) | |
| pancreatic head | 37 (31.1) | 82 (68.9) | 0.323 |
| body/tail | 39 (25.7) | 113 (74.3) | |
| Ki-67 (n = 223) | |||
| ≦2% | 45 (27.4) | 119 (72.6) | 0.580 |
| >2% | 14 (23.7) | 45 (76.3) | |
| Metastasis (n = 290) | |||
| Yes | 7 (8.9) | 72 (91.1) | 1.69 × 10−5 |
| No | 72 (34.1) | 139 (65.9) | |
| size [range] (cm) (n = 281) | 2 [1–15] | 3 [0.7–17] | 1.79 × 10−5 |