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. 2017 Mar 2;8(17):27915–27928. doi: 10.18632/oncotarget.15843

Figure 3. Pygo2 inhibits the PTX-induced apoptosis and G2/M arrest of glioma cells.

Figure 3

Cells were treated with 30 nM PTX for 48 h, and the percentage of apoptotic cells (A–B) and mitotic cells (C–D) was determined by flow cytometry after staining the cells with annexin V-FITC and PI. Decreased apoptosis rates were found in the cells expressing exogenous Pygo2 protein after treatment with PTX compared to the cells with low levels of Pygo2, and the sub-G1 index was increased in the Pygo2-knockdown cells. Data are presented as the mean ± SD of three independent experiments.