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. 2017 Mar 2;8(17):27915–27928. doi: 10.18632/oncotarget.15843

Figure 4. Pygo2 inhibits the activation of the JNK/SAPK pathway and the AP-1 and ATF2 activity.

Figure 4

(A–B) The protein levels in the stably transfected cell lines were detected by western blot analysis after treatment with 30 nM PTX for 48 h; β-actin was used as a control. (C, E) AP-1 transcription activity was examined using the reporter plasmid pAP-1-Luc. (D, F) ATF2 transcription activity was examined using the fusion trans-activator plasmid pFA-ATF2. Data are presented as the mean ± SD of three independent experiments. *P < 0.05 and **P < 0.01.