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. 2017 Mar 2;8(17):27915–27928. doi: 10.18632/oncotarget.15843

Figure 5. Pygo2 inhibits the phosphorylation of Bcl-2 and the activation of caspases.

Figure 5

(A–B) The protein levels in the stably transfected cell lines were detected by western blot analysis after treatment with 30 nM PTX in a time-dependent manner; β-actin was used as a control. (C–F) caspase-3/7 activities were measured with a Caspase-Glo® 3/7 Assay kit. (D–G) Caspase-8 activity was measured with a Caspase-Glo® 8 Assay kit. (E–H) Caspase-9 activity was measured with a Caspase-Glo® 9 Assay kit. Data are presented as the mean ± SD of three independent experiments.