Table 1. Clinical features of 138 HCC patients and Aurora A and B expression.
| Feature | Aurora A and B expression number n = 138 | p value | |||
|---|---|---|---|---|---|
| (ALBL) n = 34(25%) | (AHBL/ ALBH) n = 53(38%) | (AHBH) n = 51(37%) | |||
| YAP | 0.004 | ||||
| Low | 26 (76%) | 25 (47%) | 21 (41%) | ||
| High | 8 (24%) | 28 (53%) | 30 (59%) | ||
| Age, Years | 0.246 | ||||
| < 50 | 10 (29%) | 25 (47%) | 22 (43%) | ||
| ≥ 50 | 24 (71%) | 28 (53%) | 29 (57%) | ||
| Child-Pugh | 0.329 | ||||
| A | 33 (97%) | 47 (89%) | 45 (88%) | ||
| B | 1 (3%) | 6 (11%) | 6 (12%) | ||
| AFP, ng/ml | 0.19 | ||||
| < 20 | 12 (35%) | 13 (25%) | 21 (41%) | ||
| ≥ 20 | 22 (65%) | 40 (75%) | 30 (59%) | ||
| HBsAg | 0.051 | ||||
| (−) | 8 (24%) | 6 (11%) | 3 (6%) | ||
| (+) | 26 (76%) | 47 (89%) | 48 (94%) | ||
| Major tumor size (diameter, cm) | 0.994 | ||||
| < 5 | 15 (44%) | 24 (45%) | 23 (45%) | ||
| ≥ 5 | 19 (56%) | 29 (55%) | 28 (55%) | ||
| Number of nodules | 0.929 | ||||
| < 2 | 26 (76%) | 39 (74%) | 39 (76%) | ||
| ≥ 2 | 8 (24%) | 14 (26%) | 12 (24%) | ||
| satellites nodules | 0.467 | ||||
| NO | 6 (18%) | 13 (25%) | 15 (29%) | ||
| YES | 28 (82%) | 40 (75%) | 36 (71%) | ||
| MVI | 0.792 | ||||
| NO | 13 (38%) | 19 (36%) | 16 (31%) | ||
| YES | 21 (62%) | 34 (64%) | 35 (69%) | ||
| HBeAg | 0.532 | ||||
| (−) | 30 (88%) | 42 (79%) | 43 (84%) | ||
| (+) | 4 (12%) | 11 (21%) | 8 (16%) | ||
P < 0.05 was considered statistically significant. Pearson's chi-square test was used.
Abbreviations: YAP, Yes-associated protein; AFP, Alpha Fetal Protein; HBsAg, hepatitis B surface antigen; MVI, Microvascular invasion; HBeAg, hepatitis B e antigen.