Fig 4 is incorrect. The authors have provided a corrected version here.
Fig 4. Methylation status of CD4+CD25+CD127-IFNγ+ Treg in transplant patients and healthy controls.
Approximately, half of male kidney transplant recipients with good long-term stable graft function show mainly methylated (>75% Foxp3 TSDR methylation) IFNy+ Treg in the blood whereas the other half of male patients possess in addition a sizeable proportion of demethylated (11–75% Foxp3 TSDR methylation) IFNy+ Treg suggesting that they possess IFNy+ Treg with transient as well as stable Foxp3 expression.
Reference
- 1.Trojan K, Unterrainer C, Weimer R, Bulut N, Morath C, Aly M, et al. (2017) Helios expression and Foxp3 TSDR methylation of IFNy+ and IFNy- Treg from kidney transplant recipients with good long-term graft function. PLoS ONE 12(3): e0173773 doi:10.1371/journal.pone.0173773 [DOI] [PMC free article] [PubMed] [Google Scholar]

