Following the publication of Condliffe et al. 2016, a participant with cerebral palsy (CP‐7) was considered for re‐diagnosis to Hereditary Spastic Paraparesis after her child presented with similar bilateral, lower‐extremity spastic motor impairments. Motor unit (PSF) profiles during cutaneomuscular reflexes were not included for participant CP‐7, but data for surface EMG responses were reanalysis of the surface EMG data with CP‐7 excluded revealed that differences between the CP and NI groups remained significant. In addition, the association between spinal inhibition (I1max and I1ave) and motor function (GMFCS, FMSTOTAL and MVC) within the CP group also remained significant with similar correlation coefficients. Updated values for Table 2 are presented below with changes underlined. The original values are also presented for comparison. We also noted that there was a mistake in our transposition of some values for I1 onset and cutaneomuscular reflex termination which are also now corrected and underlined.
Updated Table 2: changes underlined
Reflex components | CP | NI | P‐value |
---|---|---|---|
I1max | −35.9 | −69.5 | <0.001 |
(Δ % BKD EMG) | (−66.7 – 68.0) | (−87.7 – −30.3) | |
I1ave | −26.1 | −48.6 | 0.001 |
(Δ % BKD EMG) | (−46.3 – 0.0) | (−63.6 – −21.7) | |
I1 onset (ms) | 52.8 | 57.4 | 0.40 |
(40.7 – 76.6) | (43.3 – 70.9) | ||
Cutaneomuscular reflex termination (ms) | 292.1 | 290.4 | 0.90 |
(175.0 – 672.6) | (186.8 – 449.1) |
Original Table 2 for comparison:
Reflex components | CP | NI | P‐value |
---|---|---|---|
I1max | −36.1 | −69.5 | <0.001 |
(Δ % BKD EMG) | (−66.7 – 68.0) | (−87.7 – −30.3) | |
I1ave | −26.4 | −48.6 | 0.001 |
(Δ % BKD EMG) | (−46.3 – 0.0) | (−63.6 – −21.7) | |
I1 onset (ms) | 58.4 | 57.4 | 0.98 |
(40.7 – 60) | (43.3 – 70.9) | ||
Cutaneomuscular reflex termination (ms) | 286 | 273 | 0.30 |
(89 – 825) | (152 – 449) |
Linked articles This article updates an earlier article by Condliffe et al. To read this article, visit https://doi.org/10.1113/JP271886.
Reference
- Condliffe EG, Jeffery DT, Emery DJ & Gorassini MA (2016). Spinal inhibition and motor function in adults with spastic cerebral palsy. J Physiol 594, 2691–2705. [DOI] [PMC free article] [PubMed] [Google Scholar]