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The Journal of Physiology logoLink to The Journal of Physiology
. 2017 Mar 10;595(11):3677–3678. doi: 10.1113/JP274128

Corrigendum

PMCID: PMC5451732  PMID: 28568768

Following publication of this article, the authors have notified The Journal of an error in the labelling of four panels in two of the figures.

The concentration of MS‐222 used for the experiments should have been 0.005%.

0.1% was the concentration of the stock solution that was used.

Since the same concentration was used to test both the larval (Figure 3) and juvenile (Figure 5) zebrafish, the authors state that the error does not change the conclusion that MS222 reduces the K+ current in juvenile (Figure 4) but not in larval (Figure 3) lateral line hair cells as reported in the paper.

Figure 3. Potassium current recordings from lateral line hair cells of the larval zebrafish before and during the local application of MS‐222.

Figure 3

A and B, Example of K+ currents recorded from a hair cell (4 dpf) before (A) and during (B) the superfusion of 0.005% MS‐222. Currents were elicited as described in Fig. 2. C, Steady‐state (measured at 160 ms) I‐V curves obtained from the recordings shown in A and B. Note that MS‐222 did not affect the K+ current amplitude, voltage or time dependence. D, Average peak and steady‐state amplitude of the K+ current at 0 mV, including those shown in A and B. Recordings are from hair cells of the larval zebrafish neuromast (3.0–5.2 dpf) in the presence (MS‐222) and absence (α‐Btx: α‐bungarotoxin) of the anaesthetic. E, Average steady‐state/peak amplitude ratio for the outward K+ current at 0 mV from the same hair cells used in panel D.

Figure 5. Current recordings from hair cells of the juvenile lateral line before and during the local application of MS‐222.

Figure 5

A–C, Example of K+ currents recorded from hair cells at 21 dpf before (A), during (B) and after (C) the local superfusion of 0.005% MS‐222. Note that MS‐222 mainly blocks the Ca2+‐activated K+ current I K,Ca and the small A‐type K+ current I A(s). I h was not affected by the anaesthetic. Currents were elicited as described in Fig. 2. D and E, Average peak and steady‐state I‐V curves for the K+ currents recorded before (D) and during (E) 0.005% MS‐222 from four hair cells of 21–26 dpf zebrafish, including the recordings shown in panels A and B. F, Peak and steady‐state currents extrapolated at 0 mV before (control) and during (MS‐222) the superfusion of the anaesthetic for the same 4 cells. Note that the peak current was significantly reduced in MS‐222. Recordings in B and C were performed at room temperature.

Reference

  1. Olt J, Johnson SL & Marcotti W (2014). In vivo and in vitro biophysical properties of hair cells from the lateral line and inner ear of developing and adult zebrafish. J Physiol 592, 2041–2058. doi: 10.1113/jphysiol.2013.265108 [DOI] [PMC free article] [PubMed] [Google Scholar]

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