Table 4.

Summary of studies reporting the effects of Mg on subjective anxiety/stress in individuals with mild to moderate hypertension.

Author	Study Design	Condition	Sample (N)	Sex	Age (year)	Treatment (s)	Control	Duration	Outcome Measure	Results	Effect Summary
Borrello et al. [70]	RCT	Mild hypertension (Diastolic BP > 90 mmHg or Systolic BP > 140 mmHg)	N = 83 (Treatment n = 42; Placebo n = 41)	30M:53F	Placebo: x = 49; Treatment: x = 51	Mg oxide 200 mg	Placebo	12 weeks	44 item Quality of Life Likert questionnaire (subscales: emotional behaviour & concerns about the future)	Significantly higher total quality of life rating after 12 weeks treatment (x = 67.58 (SD = 5)) vs. baseline (x = 73.58 (SD = 6)) & placebo (x = 73.23 (SD = 8); p < 0.05).	+
Walker et al. [64]	RCT	Mild hypertension (Diastolic BP 85–100 mmHg)	N = 36 (9 per condition)	18M:18F	Placebo: x = 49; Treatment (i): x = 53.2; Treatment (ii): x = 53; Treatment (iii): x = 48.8	(i) Mg amino acid chelate (600 mg elemental Mg/day); (ii) Hawthorn extract 500 mg; (iii) (i) + (ii) combined	Placebo (cellulose)	10 weeks	Subjective well-being questionnaire (subscales: vitality, anxiety & depression)	No significant effects on subjective well-being.	x

Mg—Magnesium; mg—milligrams; + positive treatment effect; − negative treatment effect; x no treatment effect; RCT—randomised controlled trial.