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Posttranslational modifications of p65. Schematic representation of p65 subunit of NF-κB primary structure: Rel homology domain, nuclear localization signal (NLS), activation domain (AD), transactivation domain (TAD). Amino acid residues known to be posttranslationally modified are shown; ac (acetylation), ub (ubiquitination), p (phosphorylation), me (methylation), s (symmetric methylation), a (asymmetric methylation).
