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. 2017 Mar 18;8(19):31601–31611. doi: 10.18632/oncotarget.16364

Figure 3. Azithromycin (AZM) augments expression of IFNβ in vivo at viral stimulus-induced asthma exacerbations.

Figure 3

Mice were challenged with HDM or saline 3 days/week for 3 weeks and were subsequently exposed daily for 3 days to poly(I:C) or saline. Mice were treated once daily with azithromycin or vehicle starting 48 h before and continuing throughout the poly(I:C) challenges. Lavage of the lungs was performed with PBS 24h after the final poly(I:C) exposure. Protein expression levels of IFNβ were measured by ELISA and data is presented as mean ± standard error of the mean (SEM). Comparison of different groups was performed by Kruskal-Wallis with Wilcoxon post testing. #p < 0.05; *p < 0.05 vehicle vs. AZM. 4-9 mice per group.