Table 1.
Oxycholesterol levels in white adipose tissue of mice and correlation coefficients between each oxycholesterol level and white adipose tissue weight
| Oxycholesterol levels | Correlation coefficient | ||
|---|---|---|---|
| (μg/g tissue) | r | P value | |
| Autoxidation | |||
| 7β-OH | 0.909 ± 0.404 | 0.560 | N.S. |
| 5,6β-epoxy | 2.15 ± 0.22 | −0.405 | N.S. |
| 5,6α-epoxy | 2.27 ± 0.26 | 0.218 | N.S. |
| β-triol | 1.93 ± 0.63 | 0.578 | N.S. |
| 6-keto | 1.24 ± 0.53 | 0.612 | N.S. |
| α-triol | 0.419 ± 0.217 | 0.536 | N.S. |
| 7-keto | 2.22 ± 0.29 | 0.466 | N.S. |
| Auto- and/or Enzymatic-oxidation | |||
| 7α-OH | 1.14 ± 0.58 | 0.541 | N.S. |
| 25-OH | 0.513 ± 0.262 | 0.541 | N.S. |
| Enzymatic oxidation | |||
| 4β-OH | 1.48 ± 0.41 | 0.392 | N.S. |
| 22(R)-OH | 0.100 ± 0.049 | 0.430 | N.S. |
| 24(S)-OH | 0.403 ± 0.120 | 0.454 | N.S. |
| 27-OH | 1.15 ± 0.07 | −0.727 | 0.041 |
| Total oxycholesterols | 15.9 ± 3.4 | 0.525 | N.S. |
The data are expressed as the mean ± SEM (n = 8)
4β-OH, 4β-hydroxycholesterol; 7α-OH, 7α-hydroxycholesterol; 7β-OH, 7β-hydroxycholesterol; 22(R)-OH, 22(R)-hydroxycholesterol; 22(S)-OH, 22(S)-hydroxycholesterol; 25-OH, 25-hydroxycholesterol; 27-OH, 27-hydroxycholesterol; 6-keto, 6-ketocholestanol; 7-keto, 7-ketocholesterol; 5,6α-epoxy, 5α,6α-epoxycholesterol; 5,6β-epoxy, 5β,6β-epoxycholesterol; α-triol, α-cholestantriol; β-triol, β-cholestantriol; N.S. not significant