Table 1. Quantitative analysis of ThT-monitored aggregation.

	Aβ(M1-42)			[Aβ(M1-42)]DiY			[Aβ (M1-42)]Q-k
[Aβ] (μM)	10	5	2.5	10	5	2.5	10	5	2.5
Lag Time (min)	33 ± 6	43 ± 3	80 ± 5	33 ± 11	75 ± 7	180 ± 28	2 ± 3	13 ± 6	23 ± 6
Rate (RFU/min)	185.5 ± 29.4	68.0 ± 18.3	11.0 ± 1.3	22.5 ± 0.4	15.4 ± 1.3	1.7 ± 1.3	136.0 ± 14.5	44.9 ±12.8	10.5 ± 2.2
Max Fluor. (RFU)	10869 ± 990	9963 ± 363	2618 ± 90	18660 ± 990	9963 ± 343	4400 ± 226	11110 ± 1512	4810 ± 1463	1733 ± 339
t = max	~ 5 hrs	-	-	~ 17 hrs	-	-	~ 5.5 hrs	-	-
t = ½ max	~ 1 hr	-	-	~ 6.5 hrs	-	-	~1 hr	-	-
t = ¼ max	~ 30 min	-	-	~ 3 hrs	-	-	~ 30 min	-	-

Time points were calculated based on criteria described in Supplementary Figure 4 and are the averaged from at least two separate experiments.

Values are mean ± standard deviation are given.