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. 2017 Jun 22;6:667. Originally published 2017 May 12. [Version 2] doi: 10.12688/f1000research.11432.2

Figure 3. A population of chymase positive mast cells that did not express tryptase was identified in uterine tissue samples from the mid secretory phase.

Figure 3.

The endometrial compartment shows three different mast cell (MC) subtypes: tryptase single positive, chymase single positive and tryptase and chymase double positive. Basal endometrial MCs are chymase+/tryptase- single positive and double positive, instead functional endometrium MCs are fewer in number and show a chymase-/tryptase+ phenotype. MCs during the secretory appeared to be activated in the myometrium, releasing both proteases from the cytoplasm. (n=3) (Arrowheads: MC TC cells; Vs: MC T cells; arrows: MC C cells).