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. 2017 Apr 4;8(20):33779–33795. doi: 10.18632/oncotarget.16810

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Copyright: © 2017 Rzymski et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) Growth curves of responder KG-1 cell line and non-responder MOLM-13 cell line treated with increasing concentrations of SEL120-34A (B) Time-dependent effects of 1 μM SEL120-34A in KG-1 cells. Levels of STAT5 and phosphorylated STAT5 S726 and Y694 were measured by WB. (C) STAT5 S726 inhibition after the wash-out, following 1 h treatment with 1 μM SEL120-34A. (D) Effects of prolonged SEL120-34A exposures in KG-1 cells. KG-1 were treated with SEL120-34A for 1 h, 3 days and 6 days and levels of total STAT5, STAT5 S726, STAT1 S727, Caspase 3 and Cleaved Caspase 3 were measured by WB.