Skip to main content
. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Xenotransplantation. 2017 Apr 10;24(3):10.1111/xen.12298. doi: 10.1111/xen.12298

Figure 8. Comparative analysis of memory T cell changes in draining lymph nodes between anti-CD40 Ab-treated primates and rejected controls.

Figure 8

The mean percentage of central memory(CD28+CD95+) CD4+ T cells was lower in anti-CD40 Ab-treated primates (n=4) than in rejected controls (n=2) with a marginal significance (*p=0.082, Mann-Whitney U test; C). The number of effector memory (CD28−CD95+) CD4+ and CD8+ T cells were significantly lower in anti-CD40 Ab-treated primates than in rejected controls (ζp=0.055, ζζp=0.032, Mann-Whitney U test; E). The changes of IFNγ+ CD4+ T cells was not significant. All data were analyzed after sacrifice (Anti-CD 40 treated primates > 6 months, rejected control > 1month)