Genes & Development 18: 3004-3009 (2004)

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

Javier Apfeld, Greg O'Connor, Tom McDonagh, Peter S. DiStefano, and Rory Curtis

In the above-mentioned paper, on page 3005, there are errors in the following two sentences:

We identified two AMPKα subunit homologs in C. elegans, AAK-1 and AAK-2, which are 52% and 40% identical to human AMPKα1, respectively, and are also related to the invertebrate SNF1 proteins (Fig. 2A; Supplementary Fig. 1). The kinase domains of AAK-1 and AAK-2 share 80% and 71% amino acid identity, respectively, with the kinase domain of the human AMPKα1 subunit, including conservation of a critical threonine residue whose phosphorylation is required for AMPK activation (Hardie and Hawley 2001).

They should instead read:

We identified two AMPKα subunit homologs in C. elegans, AAK-1 and AAK-2, which are 40% and 52% identical to human AMPKα1, respectively, and are also related to the invertebrate SNF1 proteins (Fig. 2A; Supplementary Fig. 1). The kinase domains of AAK-1 and AAK-2 share 71% and 80% amino acid identity, respectively, with the kinase domain of the human AMPKα1 subunit, including conservation of a critical threonine residue whose phosphorylation is required for AMPK activation (Hardie and Hawley 2001).

Due to a printer error, incorrect page numbers were cited in the above Erratum as it appeared in the print edition of the January 1, 2005, issue. The correct page numbers are cited above.