Table 6.
Baseline characteristics (% experiencing) and 1-year mortality rate for patients treated with temozolomideplus radiotherapy and radiotherapy alone, along with estimated inclusion probabilities (assuming prior model dependence defined by (5) and using the two-stage approach with τ = 0) for the analyses of the Medicare data.
| Radiotherapy only (n = 1111) |
Temozolomide (n = 776) |
Pr (Inclusion in outcome model) |
Pr (Inclusion in propensity score) |
|
|---|---|---|---|---|
| Age group: | ||||
| 65–69 | 25.6 | 30.7 | Reference | Reference |
| 70–74 | 28.1 | 32.1 | 1.00 | 0.07 |
| 75–79 | 23.8 | 23.3 | 1.00 | 0.09 |
| ≥80 | 22.5 | 13.9 | 1.00 | 0.95 |
| Gender (female/male) | 47.1 | 48.5 | 0.09 | 0.08 |
| Married (yes/no) | 64.9 | 71.0 | 0.03 | 0.03 |
| Race (white/other) | 85.4 | 89.9 | 0.10 | 0.10 |
| Income (high/low) | 63.0 | 67.8 | 1.00 | 0.23 |
| Region: | ||||
| Northeast | 21.7 | 20.3 | Reference | Reference |
| Midwest | 14.5 | 13.1 | 0.06 | 0.06 |
| South | 17.6 | 21.5 | 0.01 | 0.01 |
| West | 46.2 | 45.1 | 0.03 | 0.03 |
| Dual eligible (yes/no) | 14.3 | 11.6 | 0.02 | 0.02 |
| Biopsy (yes/no) | 31.1 | 28.9 | 0.02 | 0.02 |
| Resection (yes/no) | 73.2 | 79.1 | 1.00 | 0.48 |
| CT scan(yes/no) | 79.6 | 76.8 | 1.00 | 0.08 |
| MRI (yes/no) | 76.5 | 83.4 | 0.13 | 0.13 |
| Initial discharge (home/other) | 45.4 | 55.3 | 1.00 | 0.94 |
| Number of tumors (1 tumor/>1 tumor) | 97.5 | 98.2 | 0.02 | 0.02 |
| Location of tumors (supratentorial/other) | 77.6 | 78.5 | 0.04 | 0.04 |
| Tumor size (≥ 3cm) | 70.3 | 70.4 | 0.03 | 0.03 |
| Palliative care (yes/no) | 10.6 | 10.4 | 0.02 | 0.02 |
| Extent of resection (major/minimal) | 28.5 | 29.9 | 1.00 | 0.14 |
| Atherosclerosis (yes/no) | 17.8 | 14.4 | 0.72 | 0.05 |
| Hypertension (yes/no) | 61.5 | 61.5 | 0.02 | 0.02 |
| Cerebrovascular disease (yes/no) | 1.40 | 0.8 | 0.04 | 0.04 |
| COPD (yes/no) | 10.3 | 7.7 | 0.03 | 0.03 |
| Pneumonia (yes/no) | 1.0 | 1.3 | 0.01 | 0.01 |
| Malnutrition (yes/no) | 1.7 | 1.3 | 0.01 | 0.01 |
| Dementia (yes/no) | 7.6 | 5.9 | 0.02 | 0.02 |
| Functional disability (yes/no) | 0.3 | 0.0 | 0.02 | 0.02 |
| Prior trauma (yes/no) | 2.8 | 2.6 | 0.03 | 0.03 |
| Psychological disease (yes/no) | 2.3 | 2.1 | 0.01 | 0.01 |
| Parkinson or Huntington (yes/no) | 0.9 | 0.6 | 0.01 | 0.01 |
| Anemia (yes/no) | 8.2 | 9.1 | 0.02 | 0.01 |
| Depression (yes/no) | 5.0 | 5.2 | 0.06 | 0.05 |
| Asthma (yes/no) | 3.0 | 1.7 | 0.01 | 0.01 |
| Diabetes (yes/no) | 21.0 | 20.4 | 0.99 | 0.06 |
| Deyo score: | ||||
| 0 | 57.9 | 61.1 | Reference | Reference |
| 1 | 27.6 | 27.8 | 0.04 | 0.04 |
| 2+ | 14.5 | 11.1 | 0.01 | 0.01 |
| Death within 1-year | 75.4 | 63.7 | ||