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. 1966 Jul;14(4):649–653. doi: 10.1128/am.14.4.649-653.1966

Production of a Pyrrole Antibiotic by a Marine Bacterium1

Paul R Burkholder 1, Robert M Pfister 1, Frederick H Leitz 1,2
PMCID: PMC546803  PMID: 4380876

Abstract

Evidence is presented for the isolation and identification of bacteria able to synthesize an unusual antibiotic containing five bromine atoms per molecule. The identification and taxonomic position of these bacteria was made by use of a computer in conjunction with traditional methods. These microorganisms and closely related strains have been isolated on various occasions from tropical water in the vicinity of Puerto Rico. One bacterium, a pseudomonad, has been given the name Pseudomonas bromoutilis because of its distinctive capability. The antibiotic has been extracted, purified, and obtained in crystal form, and its structure has been determined. Although clinical tests of its properties were not encouraging, it may be of significant value and interest from an ecological standpoint.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. COLWELL R. R., LISTON J. Taxonomic relationships among the pseudomonads. J Bacteriol. 1961 Jul;82:1–14. doi: 10.1128/jb.82.1.1-14.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
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