Table 5.
One-year mortality in PICU survivors: Initial antimicrobials at trichotomous time cutoff points
| Time to Initial Antimicrobials |
Unadjusted OR (95% CI) |
Adjusted ORa
(95% CI) |
|---|---|---|
| 0 to ≤ 1 hour | 4.7 (1.1, 20.2) | 5.5 (1.1, 27.4) |
| 1 to ≤ 3 hours | Reference | Reference |
| > 3 hours | 4.1 (1.0, 16.1) | 2.2 (0.5, 11.0) |
Logistic regression analysis of one-year mortality comparing initial antimicrobial therapy at trichotomous time cutoff points from severe sepsis recognition in PICU survivors. Area under the receiver operating characteristic (AUROC) curve for the adjusted logistic regression model is 0.74 (95% CI 0.64, 0.83).
a
Adjusted for PIM2 and number of CCCs.
OR=odds ratio.
CI=confidence interval.
Total patients n=139.