Abstract
A series of three continuous cultures of Neisseria gonorrhoeae was performed at pH values ranging from 6.4 to 7.2, with an average duration of 3 weeks. The maximal yield obtained was 1.12 mg/ml at a pH of 6.75 and a dilution rate of 0.26 per hr. Some morphological variations were observed at lower dilution rates, but complement-fixation titers remained stable for the duration of the cultures.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brookes R., Hedén C. G. Dense cultures of Neisseria gonorrhoeae in liquid medium. Appl Microbiol. 1967 Mar;15(2):219–223. doi: 10.1128/am.15.2.219-223.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KELLOGG D. S., Jr, PEACOCK W. L., Jr, DEACON W. E., BROWN L., PIRKLE D. I. NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION. J Bacteriol. 1963 Jun;85:1274–1279. doi: 10.1128/jb.85.6.1274-1279.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PACKETT L. V., MCCUNE R. W. DETERMINATION OF STEAM-VOLATILE ORGANIC ACIDS IN FERMENTATION MEDIA BY GAS-LIQUID CHROMATOGRAPHY. Appl Microbiol. 1965 Jan;13:22–27. doi: 10.1128/am.13.1.22-27.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PIRT S. J. The oxygen requirement of growing cultures of an Aerobacter species determined by means of the continuous culture technique. J Gen Microbiol. 1957 Feb;16(1):59–75. doi: 10.1099/00221287-16-1-59. [DOI] [PubMed] [Google Scholar]
- REDEI A., NAGY S. Simultaneous determination of dextran and glucose in serum. Nature. 1961 Jul 8;191:173–174. doi: 10.1038/191173a0. [DOI] [PubMed] [Google Scholar]