Abstract
A series of three continuous cultures of Neisseria gonorrhoeae was performed at pH values ranging from 6.4 to 7.2, with an average duration of 3 weeks. The maximal yield obtained was 1.12 mg/ml at a pH of 6.75 and a dilution rate of 0.26 per hr. Some morphological variations were observed at lower dilution rates, but complement-fixation titers remained stable for the duration of the cultures.
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Selected References
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- Brookes R., Hedén C. G. Dense cultures of Neisseria gonorrhoeae in liquid medium. Appl Microbiol. 1967 Mar;15(2):219–223. doi: 10.1128/am.15.2.219-223.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KELLOGG D. S., Jr, PEACOCK W. L., Jr, DEACON W. E., BROWN L., PIRKLE D. I. NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION. J Bacteriol. 1963 Jun;85:1274–1279. doi: 10.1128/jb.85.6.1274-1279.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PACKETT L. V., MCCUNE R. W. DETERMINATION OF STEAM-VOLATILE ORGANIC ACIDS IN FERMENTATION MEDIA BY GAS-LIQUID CHROMATOGRAPHY. Appl Microbiol. 1965 Jan;13:22–27. doi: 10.1128/am.13.1.22-27.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PIRT S. J. The oxygen requirement of growing cultures of an Aerobacter species determined by means of the continuous culture technique. J Gen Microbiol. 1957 Feb;16(1):59–75. doi: 10.1099/00221287-16-1-59. [DOI] [PubMed] [Google Scholar]
- REDEI A., NAGY S. Simultaneous determination of dextran and glucose in serum. Nature. 1961 Jul 8;191:173–174. doi: 10.1038/191173a0. [DOI] [PubMed] [Google Scholar]